相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-κB signaling
Di Sha et al.
HUMAN MOLECULAR GENETICS (2010)
Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
Joo-Yong Lee et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Noriyuki Matsuda et al.
JOURNAL OF CELL BIOLOGY (2010)
A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation
Jurre Hageman et al.
MOLECULAR CELL (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
Cristofol Vives-Bauza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
Der-Fen Suen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
Elena Ziviani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
Ruben K. Dagda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
Hui Xiong et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant α-Synuclein
Xiao-Hong Lu et al.
JOURNAL OF NEUROSCIENCE (2009)
DnaJB6 Is Present in the Core of Lewy Bodies and Is Highly Up-Regulated in Parkinsonian Astrocytes
P. F. Durrenberger et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Converging concepts of protein folding in vitro and in vivo
F. Ulrich Hartl et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function
Eleanor J. Davison et al.
PROTEOMICS (2009)
Photoreceptor IFT Complexes Containing Chaperones, Guanylyl Cyclase 1 and Rhodopsin
Reshma Bhowmick et al.
TRAFFIC (2009)
Mitochondrial Function and Morphology Are Impaired in parkin-Mutant Fibroblasts
Heather Mortiboys et al.
ANNALS OF NEUROLOGY (2008)
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
Yongsung Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig et al.
EMBO JOURNAL (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies
Lynn Bedford et al.
JOURNAL OF NEUROSCIENCE (2008)
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
Hansong Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The effects of oxidative stress on parkin and other E3 ligases
Matthew J. LaVoie et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease
J. L. Howarth et al.
MOLECULAR THERAPY (2007)
Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations
Esther S. P. Wong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
Cornelia Hampe et al.
HUMAN MOLECULAR GENETICS (2006)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase
M Borrell-Pagès et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Parkin enhances mitochondrial biogenesis in proliferating cells
Y Kuroda et al.
HUMAN MOLECULAR GENETICS (2006)
Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease
LB Moran et al.
NEUROGENETICS (2006)
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function
C Wang et al.
HUMAN MOLECULAR GENETICS (2005)
Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition
R Bandopadhyay et al.
NEUROBIOLOGY OF DISEASE (2005)
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin
SR Sriram et al.
HUMAN MOLECULAR GENETICS (2005)
HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome
B Westhoff et al.
CURRENT BIOLOGY (2005)
Hsp70 chaperones: Cellular functions and molecular mechanism
MP Mayer et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: Implications for Lewy body formation
KL Lim et al.
JOURNAL OF NEUROSCIENCE (2005)
Neuronal DnaJ proteins HSJ1a and HSJ1b: a role in linking the Hsp70 chaperone machine to the ubiquitin-proteasome system?
JP Chapple et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates
WJ Gu et al.
NEUROBIOLOGY OF DISEASE (2003)
Inactivation of parkin by oxidative stress and C-terminal truncations - A protective role of molecular chaperones
KF Winklhofer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
RING finger 1 mutations in Parkin produce altered localization of the protein
MR Cookson et al.
HUMAN MOLECULAR GENETICS (2003)
Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin
HC Ardley et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
The chaperone environment at the cytoplasmic face of the endoplasmic reticulum can modulate rhodopsin processing and inclusion formation
JP Chapple et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
JC Greene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
F Darios et al.
HUMAN MOLECULAR GENETICS (2003)
Parkin accumulation in aggresomes due to proteasome impairment
E Junn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
Y Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
Y Imai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura et al.
NATURE GENETICS (2000)