相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure
B. Blairanne Williams et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels
Rong Yuan et al.
AGING CELL (2009)
Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington's disease
Andreas Weiss et al.
ANALYTICAL BIOCHEMISTRY (2009)
Sustained Effects of Nonallele-Specific Huntingtin Silencing
Valerie Drouet et al.
ANNALS OF NEUROLOGY (2009)
Progress and Challenges in RNA Interference Therapy for Huntington Disease
Scott Q. Harper
ARCHIVES OF NEUROLOGY (2009)
Short-term oral oestrogen therapy dissociates the growth hormone/insulin-like growth factor-I axis without altering energy metabolism in premenopausal women
Denise S. Huang et al.
GROWTH HORMONE & IGF RESEARCH (2009)
Beyond the brain: widespread pathology in Huntington's disease
Jorien M. M. van der Burg et al.
LANCET NEUROLOGY (2009)
Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice
Ryan L. Boudreau et al.
MOLECULAR THERAPY (2009)
Neuroendocrine Disturbances in Huntington's Disease
Nadine Saleh et al.
PLOS ONE (2009)
Reference ranges of serum IGF-1 and IGFBP-3 levels in a general adult population:: Results of the Study of Health in Pomerania (SHIP)
Nele Friedrich et al.
GROWTH HORMONE & IGF RESEARCH (2008)
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease
Chuan-En Wang et al.
HUMAN MOLECULAR GENETICS (2008)
Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry
Heike Runne et al.
JOURNAL OF NEUROSCIENCE (2008)
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
Michelle Gray et al.
JOURNAL OF NEUROSCIENCE (2008)
Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease
Xin Wang et al.
JOURNAL OF NEUROSCIENCE (2008)
Weight loss in Huntington disease increases with higher CAG repeat number
N. A. Aziz et al.
NEUROLOGY (2008)
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits
M. DiFiglia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease
Mary Y. Heng et al.
JOURNAL OF NEUROSCIENCE (2007)
Early Energy Deficit in Huntington Disease: Identification of a Plasma Biomarker Traceable during Disease Progression
Fanny Mochel et al.
PLOS ONE (2007)
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates
Annette Dalrymple et al.
JOURNAL OF PROTEOME RESEARCH (2007)
Huntington's disease:: from huntingtin function and dysfunction to therapeutic strategies
M. Borrell-Pages et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
Body weight is modulated by levels of full-length Huntingtin
JM Van Raamsdonk et al.
HUMAN MOLECULAR GENETICS (2006)
Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models
RK Graham et al.
NEUROBIOLOGY OF DISEASE (2006)
Cleavage pattern and emerging asymmetry of the mouse embryo
MZ Zernicka-Goetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA
YL Wang et al.
NEUROSCIENCE RESEARCH (2005)
Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice
E Rodriguez-Lebron et al.
MOLECULAR THERAPY (2005)
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions
EJ Slow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Gene expression in Huntington's disease skeletal muscle: a potential biomarker
AD Strand et al.
HUMAN MOLECULAR GENETICS (2005)
Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease
JM Van Raamsdonk et al.
HUMAN MOLECULAR GENETICS (2005)
RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model
SQ Harper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Assessment of the nutrition status of patients with Huntington's disease
A Trejo et al.
NUTRITION (2004)
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
LR Gauthier et al.
CELL (2004)
A PCR primer bank for quantitative gene expression analysis
XW Wang et al.
NUCLEIC ACIDS RESEARCH (2003)
Depletion of wild-type huntingtin in mouse models of neurologic diseases
YU Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
C Zuccato et al.
NATURE GENETICS (2003)
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
EJ Slow et al.
HUMAN MOLECULAR GENETICS (2003)
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
S Sipione et al.
HUMAN MOLECULAR GENETICS (2002)
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
R Luthi-Carter et al.
HUMAN MOLECULAR GENETICS (2002)
Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
R Luthi-Carter et al.
HUMAN MOLECULAR GENETICS (2002)
Lessons from animal models of Huntington's disease
DC Rubinsztein
TRENDS IN GENETICS (2002)
The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin
W Auerbach et al.
HUMAN MOLECULAR GENETICS (2001)
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
C Zuccato et al.
SCIENCE (2001)
Neurological abnormalities in a knock-in mouse model of Huntington's disease
CH Lin et al.
HUMAN MOLECULAR GENETICS (2001)
Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells
F Trettel et al.
HUMAN MOLECULAR GENETICS (2000)
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
I Dragatsis et al.
NATURE GENETICS (2000)
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
A Yamamoto et al.
CELL (2000)