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ACTA NEUROPATHOLOGICA (2008)
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Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations
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Axonal abnormalities in cerebellar Purkinje cells of the Ts65Dn mouse
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Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome
Tomohiko Sato et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
Fei Liu et al.
FASEB JOURNAL (2008)
Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination
Arnaud Duchon et al.
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Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome
Jianhua Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease
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Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A
Sergi Aranda et al.
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Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome
Dani Bercovich et al.
LANCET (2008)
Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome
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Trisomy represses ApcMin-mediated tumours in mouse models of Down's syndrome
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Large recurrent microdeletions associated with schizophrenia
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Identification of loci associated with schizophrenia by genome-wide association and follow-up
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Common variants near MC4R are associated with fat mass, weight and risk of obesity
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Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons
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Prevention of Developmental Delays in a Down Syndrome Mouse Model
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Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test
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Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome
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Characterization of the cardiac phenotype in neonatal Ts65Dn mice
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Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome:: an iBFM-SG study
Erik Forestier et al.
BLOOD (2008)
DYRK1A-mediated hyperphosphorylation of Tau - A functional link between Down syndrome and Alzheimer disease
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Synaptic and cognitive abnormalities in mouse models of down syndrome: Exploring genotype-phenotype relationships
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Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
Joongkyu Park et al.
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Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain
A. Nistor et al.
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Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome
Joseph. H. Lee et al.
NEUROSCIENCE LETTERS (2007)
Trisomy of chromosome 21 in leukemogenesis
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BLOOD CELLS MOLECULES AND DISEASES (2007)
Classification of human chromosome 21 gene-expression variations in down syndrome:: Impact on disease phenotypes
E. Ait Yahya-Graison et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses
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AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance
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National estimates and race/ethnic-specific variation of selected birth defects in the United States, 1999-2001
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DYRKIA BAC transgenic mice show altered synaptic plasticity with learning and memory defects
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NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
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