相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Characterizing genetic variants for clinical action
Erin M. Ramos et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2014)
In silico comparative characterization of pharmacogenomic missense variants
Biao Li et al.
BMC GENOMICS (2014)
Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer
Hiltrud Brauch et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)
Clinical Interpretation and Implications of Whole-Genome Sequencing
Frederick E. Dewey et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
Milestone approval lifts Illumina's NGS from research into clinic
Cormac Sheridan
NATURE BIOTECHNOLOGY (2014)
Functional annotation of noncoding sequence variants
Graham R. S. Ritchie et al.
NATURE METHODS (2014)
The European Bioinformatics Institute's data resources 2014
Catherine Brooksbank et al.
NUCLEIC ACIDS RESEARCH (2014)
ClinVar: public archive of relationships among sequence variation and human phenotype
Melissa J. Landrum et al.
NUCLEIC ACIDS RESEARCH (2014)
MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing
Matthew Mort et al.
GENOME BIOLOGY (2014)
Genotype-Guided vs Clinical Dosing of Warfarin and Its Analogues Meta-analysis of Randomized Clinical Trials
Kathleen Stergiopoulos et al.
JAMA INTERNAL MEDICINE (2014)
Clinical Pharmacogenomics: Opportunities and Challenges at Point of Care
S. A. Scott
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Wo steht die Pharmakogenetik nach 30 Jahren Forschung?
M. Eichelbaum
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT (2013)
Pharmacogenetics of warfarin: challenges and opportunities
Ming Ta Michael Lee et al.
JOURNAL OF HUMAN GENETICS (2013)
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
Joshua C. Denny et al.
NATURE BIOTECHNOLOGY (2013)
Cancer pharmacogenomics: strategies and challenges
Heather E. Wheeler et al.
NATURE REVIEWS GENETICS (2013)
A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon
Talitha I. Verhoef et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing
Stephen E. Kimmel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
A Randomized Trial of Genotype-Guided Dosing of Warfarin
Munir Pirmohamed et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
PharmGKB summary: tamoxifen pathway, pharmacokinetics
Daniel J. Klein et al.
PHARMACOGENETICS AND GENOMICS (2013)
Genome-wide association studies in pharmacogenomics: successes and lessons
Alison A. Motsinger-Reif et al.
PHARMACOGENETICS AND GENOMICS (2013)
Implementation of a clinical research pharmacogenomics program at an academic medical center: role of the genetics healthcare professional
Amy Curry Sturm et al.
PHARMACOGENOMICS (2013)
Cancer Pharmacogenomics: Early Promise, But Concerted Effort Needed
Howard L. McLeod
SCIENCE (2013)
Translating pharmacogenomics discoveries into the clinic: an implementation framework
R. Stephanie Huang et al.
GENOME MEDICINE (2013)
The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system
Neda Gharani et al.
GENOME MEDICINE (2013)
Phenome-Wide Association Studies on a Quantitative Trait: Application to TPMT Enzyme Activity and Thiopurine Therapy in Pharmacogenomics
Antoine Neuraz et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Using Genome-Wide Association Studies to Identify Genes Important in Serious Adverse Drug Reactions
Ann K. Daly
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Implementing Personalized Medicine: Development of a Cost-Effective Customized Pharmacogenetics Genotyping Array
J. A. Johnson et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
Operational Implementation of Prospective Genotyping for Personalized Medicine: The Design of the Vanderbilt PREDICT Project
J. M. Pulley et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era
Marylyn D. Ritchie
HUMAN GENETICS (2012)
FIRST PHARMACOGENOMIC ANALYSIS USING WHOLE EXOME SEQUENCING TO IDENTIFY NOVEL GENETIC DETERMINANTS OF CLOPIDOGREL RESPONSE VARIABILITY: RESULTS OF THE GENOTYPE INFORMATION AND FUNCTIONAL TESTING (GIFT) EXOME STUDY
Matthew J. Price et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Assessment of Thiopurine S-Methyltransferase Activity in Patients Prescribed Thiopurines: A Systematic Review
Ronald A. Booth et al.
ANNALS OF INTERNAL MEDICINE (2011)
The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
Catherine A. McCarty et al.
BMC MEDICAL GENOMICS (2011)
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing
J. A. Johnson et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Pharmacogenetics: From Bench to Byte-An Update of Guidelines
J. J. Swen et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network
M. V. Relling et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Prediction of Functional Regulatory SNPs in Monogenic and Complex Disease
Yiqiang Zhao et al.
HUMAN MUTATION (2011)
Pharmacogenomics in the Assessment of Therapeutic Risks versus Benefits: Inside the United States Food and Drug Administration
Issam Zineh et al.
PHARMACOTHERAPY (2011)
PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
Joshua C. Denny et al.
BIOINFORMATICS (2010)
Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17
Alain Li-Wan-Po et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Challenges in the clinical application of whole-genome sequencing
Kelly E. Ormond et al.
LANCET (2010)
Clinical assessment incorporating a personal genome
Euan A. Ashley et al.
LANCET (2010)
Genetic testing clamp down
Malorye Allison
NATURE BIOTECHNOLOGY (2010)
Genome-wide association studies in pharmacogenomics
Ann K. Daly
NATURE REVIEWS GENETICS (2010)
The Canadian Pharmacogenomics Network for Drug Safety: A Model for Safety Pharmacology
Colin J. D. Ross et al.
THYROID (2010)
Automated inference of molecular mechanisms of disease from amino acid substitutions
Biao Li et al.
BIOINFORMATICS (2009)
Pharmacogenomic genome-wide association studies: lessons learned thus far
J. J. Crowley et al.
PHARMACOGENOMICS (2009)
Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease
Javier P. Gisbert et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
Irinotecan pharmacogenetics:: Influence of pharmacodynamic genes
Janelle M. Hoskins et al.
CLINICAL CANCER RESEARCH (2008)
Pharmacogenomics: candidate gene identification, functional validation and mechanisms
Liewei Wang et al.
HUMAN MOLECULAR GENETICS (2008)
PharmGKB and the international warfarin pharmacogenetlics consortium: The changing role for pharmacogenomic databases and single-drug pharmacogenetics
Ryan P. Owen et al.
HUMAN MUTATION (2008)
In silico and in vitro pharmacogenetic analysis in mice
Yinglying Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Pharmacogenetics Research Network: From SNP discovery to clinical drug response
K. M. Giacomini et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
In silico pharmacogenetics of warfarin metabolism
YY Guo et al.
NATURE BIOTECHNOLOGY (2006)
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity
M Ingelman-Sundberg
PHARMACOGENOMICS JOURNAL (2005)
Drug therapy - Pharmacogenomics - Drug disposition, drug targets, and side effects
WE Evans et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Patterns of linkage disequilibrium in the human genome
KG Ardlie et al.
NATURE REVIEWS GENETICS (2002)
Potential role of pharmacogenomics in reducing adverse drug reactions - A systematic review
KA Phillips et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)