期刊
HUMAN BRAIN MAPPING
卷 30, 期 4, 页码 1387-1396出版社
WILEY
DOI: 10.1002/hbm.20608
关键词
electroencephalography; motor cortex; prefrontal cortex; reproducibility; transcranial magnetic stimulation
Navigated transcranial magnetic stimulation combined with electroencephalography (nTMS-EEG), allows noninvasive studies of cortical excitability and connectivity in humans. We investigated the reproducibility of nTMS-EEG in seven healthy subjects by repeating left motor and prefrontal cortical stimulation with a 1-week interval. TMS,vas applied at three intensities: 90, 100, and 110% of subjects' motor threshold (NIT). The TMS-compatible neuronavigation system guaranteed precise repositioning of the stimulation coil. The responses were recorded by a 60-channel whole head TMS-compatible EEG amplifier. A high overall reproducibility (r > 0.80) was evident in nTMS-EEG responses over both hemispheres for both motor and prefrontal cortical stimulation. The results suggest that nTMS-EEG is a reliable tool for studies investigating cortical excitability changes in the test-retest designs. Hum Brain Mapp 30:1387-1396, 2009. (C) 2008 Wiley-Liss, Inc.
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