期刊
HUMAN & EXPERIMENTAL TOXICOLOGY
卷 29, 期 1, 页码 37-47出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327109354312
关键词
Cannabis leaves; bango; lethal dose 50
类别
资金
- Assiut University
Cannabis is the most commonly abused drug in the world. In Egypt, the Anti Narcotic General Administration showed that the narcotics problem costs the Egyptian economy approximately 800 million dollars annually. LD(50), lethal dose that kills 50% of the treated animals, of the bango was determined and then selected groups of rats were given tenth of LD(50) for 90 days. The histopathological effects were determined. All the studied organs were affected markedly in the form of shrunken cells in brain. The liver cells were affected in the form of rarefaction of the cytoplasm, kidneys were with severe congestion. The testicles were with disruption of the spermatogenic cells from the membrane.
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