期刊
LANGMUIR
卷 31, 期 46, 页码 12567-12572出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.langmuir.5b02559
关键词
-
资金
- PRESTO grant from Japan Science and Technology Agency
- Hakubi Center
- WPI-iCeMS
- Opto-Science Foundation
- Inamori Foundation
- Grants-in-Aid for Scientific Research [26560209] Funding Source: KAKEN
Noncontact manipulation of nano/micromaterials presents a great challenge in fields ranging from biotechnology to nanotechnology. In this study we developed a new strategy for the manipulation of molecules and cells based on diffusiophoresis driven by a concentration gradient of a polymer solute. By using laser focusing in a microfluidic device, we created a sharp concentration gradient of poly(ethylene glycol) (PEG) in a solution of this polymer. Because diffusiophoresis essentially depends on solute gradients alone, PEG solute contrast resulted in trapping of DNA and eukaryotic cells with little material dependence. Furthermore, quantitative analysis revealed that the motility of migrating cells was enhanced with the PEG concentration, consistent with a theoretical model of boosted cell migration. Our results support that a solute contrast of polymer can exert an interfacial force gradient that physically propels objects and may have application for the manipulation of soft materials.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据