Transport through the Golgi in Trypanosoma brucei

The mechanism of transport through the Golgi is still controversial, and this has led to a search for model organisms that might provide new insights. One such is the protozoan parasite, Trypanosoma brucei, which has a single Golgi whose major cargo is the GPI-anchored coat proteins that decorate the cell surface and protect the organism against immune attack through a shedding mechanism. Using published biochemical and stereological data, it is possible to show that some models for Golgi transport appear more likely than others.