期刊
HETEROCYCLES
卷 84, 期 2, 页码 1013-1021出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-11-S(P)79
关键词
Formic Acid Cyclization; Alkyne Acetal; Hydrogenated Pyridine, Furan, Pyrrole, and Quinoline; 2H-Chromene; Benzoxepin-5(2H)-one
资金
- EPSRC [EP/G068313/1]
- AstraZeneca
- Engineering and Physical Sciences Research Council [EP/G068313/1] Funding Source: researchfish
- EPSRC [EP/G068313/1] Funding Source: UKRI
The utility of formic acid for the cyclisation of alkyne omega-acetals is described; the scope and limitations of this process are outlined and a range of acylated heterocyclic building blocks (2,5-dihydrofurans, 2,5-dihydro-1H-pyrroles, tetrahydropyridines, 2H-chromenes, 1,2-dihydroquinolines and benzoxepin5-(2H)-ones) are reported.
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