期刊
HETEROCYCLES
卷 85, 期 7, 页码 1629-+出版社
Japan Inst Heterocyclic Chemistry
DOI: 10.3987/COM-12-12494
关键词
Catalyst Free; One-Pot Synthesis; Environmental-Friendly conditions
资金
- Department of Chemistry, IIT Roorkee through MHRD, New Delhi
An efficient one-pot, three-component synthesis method of highly functionalized coumarin fused 7,13-dihydro-5-oxa-13-aza-indeno[2,1-b]phenanthrene and chromeno[4,3-b]quinoline derivatives was accomplished using aromatic aldehyde, 4-aminocoumarin and cyclic 1,3-dione in acetic acid at reflux temperature. Environmental-friendly protocol has advantages of high yields, creating three new bonds and one stereocenter in single operation. Further, XRD and DFT study confirmed the molecular structure, stability and different interaction in the crystal packing.
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