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MICROWAVE ASSISTED SYNTHESIS OF FUSED HETEROCYCLIC COMPOUNDS

期刊

HETEROCYCLES
卷 83, 期 11, 页码 2451-2488

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/REV-11-696

关键词

Microwave Assisted Synthesis; Five Membered Fused Heterocycle

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Microwave assisted heating under controlled conditions has been proved beneficial for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes or even seconds. Also, microwave synthesis provides higher yields, lower cost, easy workups and greater purity as compared to lower yields, tedious workups, longer reaction times, lesser purity and termination of many by-products in the conventional thermal methods.

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