期刊
HETEROCYCLES
卷 81, 期 4, 页码 991-996出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-09-11899
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资金
- NMMBA [981001101, 99200321, 99200322]
- APORC, NSYSU [96C031702]
- NDHU
- NSTPBP, National Science Council, Taiwan [NSC 98-2323-B-291-001, NSC 98-2320-B-291-001-MY3]
A new chlorinated briarane-type diterpenoid, 12-epi-fragilide G (I), was isolated from the gorgonian coral Ellisella robusta. The structure of 1 was elucidated by the interpretations of spectral data analysis and this compound was found to possess an s-cis diene moiety in its structure. Briarane 1 displayed inhibitory effects on elastase release by human neutrophils.
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