期刊
HETEROCYCLES
卷 78, 期 10, 页码 2595-2600出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-09-11771
关键词
Echinomuricea; Curcuphenol; Gorgonian; Superoxide Anion; Elastase
资金
- NMMBA [981001101]
- NDHU
- APORC
- NSYSU
- NSTPBP
- National Science Council, Taiwan [NSC 97-2323-B-291-001, NSC 98-2320-B-291-001-MY3]
Two sesquiterpenoid phenols, including a new natural product 1 [(7S, 10R)-(+)-10,11-epoxycurcuphenol] and a known metabolite, (+)-curcuphenol (2), were isolated from a gorgonian coral identified as Echinomuricea sp. The structures of 1 and 2 were elucidated by interpretations of spectral data and by comparison of the related physical and spectral data with those of related metabolites. Compound 2 was found to show significant inhibitory effects on elastase release by human neutrophils.
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