期刊
HETEROCYCLES
卷 76, 期 2, 页码 1049-1055出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-08-S(N)105
关键词
Organocatalyst; Asymmetric Catalyst; Enantioselectivity; Bronsted Base
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan [19020006]
- Japan Society for the Promotion of Science
- Grants-in-Aid for Scientific Research [19020006] Funding Source: KAKEN
The enantioselective epoxidation of alpha,beta-unsaturated ketones with hydrogen peroxide was demonstrated using axially chiral guanidine as a base catalyst. Hydrogen peroxide can be utilized as a cost-effective and atom-efficient oxidant in the present catalytic epoxidation even under heterogeneous conditions. The newly developed axially chiral guanidine base bearing an additional central chirality functions as an efficient catalyst to provide epoxides in 51-65% ee.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据