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S. Vallet et al.
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Hari S. Conjeevaram et al.
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Y. Sato et al.
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Susan L. Uprichard et al.
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Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein
K Saito et al.
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Modulation of the transforming growth factor-β signal transduction pathway by hepatitis C virus nonstructural 5A protein
SH Choi et al.
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Y Rouillé et al.
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Y Hara et al.
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Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
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S Yagi et al.
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T Ozaki et al.
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A Kasprzak et al.
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A Schulze-Krebs et al.
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Robust hepatitis C virus infection in vitro
J Zhong et al.
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Effect of hepatitis C virus nonstructural protein NS3 on proliferation and MAPK phosphorylation of normal hepatocyte line
De-Yun Feng et al.
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Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular β-catenin and stimulation of β-catenin-responsive transcription
A Street et al.
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M Hassan et al.
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T Heller et al.
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CT Yeh et al.
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K Otani et al.
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S de Lucas et al.
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R Suzuki et al.
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B Sarcar et al.
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A Macdonald et al.
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R Bataller et al.
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A Hosui et al.
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J Roussel et al.
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S Ogata et al.
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HJ Kwun et al.
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V Falcón et al.
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A Macdonald et al.
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A Alisi et al.
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QQ He et al.
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SY Chen et al.
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ZM Xu et al.
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HM Soo et al.
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D Kumar et al.
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I Qadri et al.
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S Ogata et al.
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M Dubourdeau et al.
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T Yoshida et al.
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MN Lee et al.
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YP He et al.
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KH Lan et al.
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A Basu et al.
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T Yamanaka et al.
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D Egger et al.
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HJ Han et al.
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M Okuda et al.
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G Mottola et al.
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HJ Kwun et al.
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SJ Polyak et al.
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M Giménez-Barcons et al.
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NL Zhu et al.
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N Arima et al.
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KJ Park et al.
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JW Cho et al.
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R Zemel et al.
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R Suzuki et al.
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G Martire et al.
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J Hayashi et al.
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H Aoki et al.
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