期刊
HEPATOLOGY INTERNATIONAL
卷 7, 期 -, 页码 S771-S781出版社
SPRINGER
DOI: 10.1007/s12072-013-9468-6
关键词
NAFLD; NASH; Inflammation; PAMPs; DAMPs; Immunity
Immune and inflammatory pathways have a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Both the innate and adaptive immune systems contribute to the development of NAFLD. Pathogen-associated molecular patterns and danger-associated molecular patterns are known to activate a variety of pattern-recognition receptors that result in inflammation. The key features of the immune system and inflammatory pathways in the development of NAFLD are discussed in this review.
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