期刊
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
卷 23, 期 1, 页码 109-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.hoc.2008.11.003
关键词
Gastrointestinal stromal tumor; Perifosine; Imatinib mesylate; Ulcerative keratitis; Periorbital edema
Imatinib mesylate and perifosine are two relatively new drugs that have improved outcomes for patients with gastrointestinal stromal tumors in recent years. The ocular side effects of these two drugs are discussed,in this chapter. The most common ocular side effect associated with imatinib mesylate is periorbital edema. Perifosine has been associated with a ring-shaped perilimbal corneal ulceration that can be treated with topical steroids and topical antibiotics.
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