期刊
HELVETICA CHIMICA ACTA
卷 94, 期 4, 页码 623-631出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.201000283
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资金
- Bundesministerium fur Bildung und Forschung (BMBF)
- MOST
- Alfried Krupp von Bohlen and Halbach Foundation
Chemical examination of the fungus Aspergillus ustus isolated from the Mediterranean sponge Suberites domuncula yielded the five new ophiobolin-type sesterterpenoids 1-5 and the two new pyrrolidine alkaloids 6 and 7, together with the known compound aurantiamine and cerebroside D. The structures of the new compounds were unambiguously elucidated on the basis of extensive spectroscopic-data analysis (1D- and 2D-NMR, MS, and UV) and comparison with literature data. All compounds were evaluated for their cytotoxicity against murine lymphoma cell line L5178Y.
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