One-Pot Synthesis of 5-Substituted 1H-Tetrazoles from Aryl Bromides with Potassium Hexakis(cyano-kappa C)ferrate(4-) (K-4[Fe(CN)(6)]) as Cyanide Source

A one-pot procedure for the synthesis of 5-Substituted 1H-Tetrazoles through the three-component reaction between an aryl bromide, potassium hexakis(cyano-kappa C)ferrate(4-) (K-4[Fe(CN)(6)]) and NaN3 catalyzed by [Pd(OAc)(2)] and ZnBr2 in the presence of 1,4-diazabicyclo[2.2.2]octane (dabco) was developed. Furthermore, the reaction occurred under nonacidic conditions and involved a nontoxic cyanide source, making this method a quite attractive one.