4.4 Article

Efforts to enhance catheter stability improve atrial fibrillation ablation outcome

期刊

HEART RHYTHM
卷 10, 期 3, 页码 347-353

出版社

ELSEVIER SCIENCE INC
DOI: 10.1016/j.hrthm.2012.10.044

关键词

Catheter ablation; Atrial fibrillation; High-frequency jet ventilation

资金

  1. F. Harlan Batrus Research Fund
  2. Murray and Susan Bloom Research Fund

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BACKGROUND Contemporary techniques to enhance anatomical detail and catheter contact during atria l fibrillation (AF) ablation include (1) the integration of preacquired tomographic reconstructions with electroanatomical mapping (3-dimensional image integration [I-EAM]), (2) the use of steerable introducers (SIs), and (3) high-frequency jet ventilation (HFJV). OBJECTIVE To prove that using these stabilizing techniques during AF ablation improves 1-year procedural outcome. METHODS We studied 300 patients undergoing AF ablation at our institution. Patients were divided into 3 equal treatment groups (100 patients each) on the basis of the took utilized: (1) group 1: AF ablation performed without I-EAM, SI, or HFJV; (2) group 2: AF ablation performed using I-EAM and SI, but without HFJV; and (3) group 3: AF ablation performed with I-EAM, SI, and HFJV. The primary outcome was freedom from AF 1 year after a singe ablation procedure. The burden of both acute and chronic pulmonary vein reconnection was also assessed. RESULTS Patients from groups 2 and 3 had significantly more nonparoxysmal AF (17% vs 30% vs 39%; P = .002), larger left atria (4.2 +/- 0.8 cm vs 4.4 +/- 0.7 cm vs 4.5 +/- 0.8 cm; P < .001), and higher body mass index (BMI; 28.5 +/- 5.8 kg/m(2) vs 29.1 +/- 4.8 kg/m(2) vs 31.2 +/- 5.4 kg/m(2); P < .001). Despite these differences, with adoption of I-EAM, SI, and HEW we noted a significant improvement in 1-year freedom from AF (52% vs 66% vs 74%; P = .006) as well as fewer acute (1.1 +/- 1.2 vs 0.9 +/- 1.1 vs 0.6 +/- 0.9; P = .03) and chronic (3.5 +/- 0.9 vs 3.2 +/- 0.9 vs 2.4 +/- 1.0; P = .02) pulmonary vein reconnections. CONCLUSIONS The incorporation of contemporary took to enhance anatomical detail and ablation catheter stability significantly improved 1-year freedom from AF after ablation.

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