4.7 Article

Step-emulsification in a microfluidic device

期刊

LAB ON A CHIP
卷 15, 期 4, 页码 1023-1031

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4lc01289e

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资金

  1. Israel Science Foundation (ISF) [1319/09]
  2. Joliot Chair visiting position at the Ecole Superieure de Physique et Chimie de Paris (ESPCI)
  3. CNRS
  4. ESPCI

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We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.

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