期刊
HEARING RESEARCH
卷 256, 期 1-2, 页码 58-63出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.heares.2009.06.015
关键词
Auditory systems; Vestibular system; Hair cells; Otolithic membrane; Bullfrog sacculus; High-speed imaging
资金
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [0920696] Funding Source: National Science Foundation
High-speed imaging with a CMOS camera was used to track the motion of multiple hair bundles of the bullfrog sacculus. To maintain the natural degree of intercell coupling, the overlying otolithic membrane was left intact atop the in vitro preparation. Effects of an incoming mechanical signal were mimicked by laterally deflecting the membrane with a glass probe at physiological amplitudes. The motion evoked in the underlying hair bundles was found to be highly phase-locked, yielding an entrained response across hundreds of cells. We imaged significant portions of the saccular epithelium, up to 40 x 350 mu m(2), and observed a high degree of correlation over those scales. Published by Elsevier B.V.
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