期刊
HEADACHE
卷 54, 期 3, 页码 459-471出版社
WILEY
DOI: 10.1111/head.12297
关键词
headache; migraine; obesity; body mass index
资金
- NINDS NIH HHS [K23 NS078345, R01 NS077925] Funding Source: Medline
Obesity and headache are both associated with a substantial personal and societal impact, and epidemiologic studies have consistently identified a positive association between obesity and headache in general, as well as obesity and migraine specifically (see part I). In the current manuscript, we will discuss the potential mechanisms for the migraine-obesity association, with a focus on the central and peripheral pathophysiological pathways which overlap between migraine and those modulating the drive to feed. We then discuss surgical, behavioral, and pharmacological treatment considerations for overweight and obese migraineurs as well as for those with idiopathic intracranial hypertension. We close by briefly discussing where future research may be headed in light of this data.
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