期刊
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
卷 37, 期 3, 页码 413-417出版社
WILEY
DOI: 10.1002/hed.23617
关键词
nasopharyngeal carcinoma; allergic rhinitis; cohort study; National Health Insurance; National Health Insurance Research Database
资金
- Taiwan Ministry of Health and Welfare Clinical Trial and Research Center for Excellence [DOH102-TD-B-111-004]
- Taiwan Ministry of Health and Welfare Cancer Research Center for Excellence [MOHW103-TD-B-111-03]
- International Research-Intensive Centers of Excellence in Taiwan (I-RiCE) [NSC101-2911-I-002-303]
- [DMR-103-012]
- [DMR-103-018]
BackgroundThe purpose of this study was to examine the risk of nasopharyngeal carcinoma (NPC) after a diagnosis of allergic rhinitis. MethodsWe identified 67,532 patients with allergic rhinitis (allergic rhinitis cohort) and a 135,064 control cohort with the same mean age and sex ratio by using a Taiwan Longitudinal Health Insurance Database (LHID) sample from 2000 to 2005. ResultsAfter adjusting for the possible confounding factors of the study, the allergic rhinitis cohort had a 2.33-fold higher risk of developing NPC than did the comparison cohort. The frequency of allergic rhinitis visits was correlated with the risk of subsequent NPC. Patients with 4 or more allergic rhinitis visits per year were significantly associated with increasingly developing NPC risk. ConclusionPatients with allergic rhinitis might be associated with subsequent NPC in Taiwan. Those who had repeated visits for allergic rhinitis had even higher risk for NPC. Physicians should be aware of the link when assessing patients with allergic rhinitis. (c) 2014 Wiley Periodicals, Inc. Head Neck 37: 413-417, 2015
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