Synthesis and characterization of polyrotaxane based on mono-6-tosyl-β -cyclodextrin

作者

Chaijun Lee¹ , Jihyun Lee¹ , Jinwoong Jung² , Ildoo Chung¹

1. Pusan National University
2. Dongah Chemical Co

会议/活动

The 8th Asian Symposium on Advanced Materials (ASAM-8), July 2023 (Novosibirsk, Russian Federation)

海报摘要

β-Cyclodextrin(β-CD) is a type of cyclic oligosaccharide used in various fields such as drug delivery, gene therapy, catalyst, chemical sensor, and liquid crystal. Mono-6-deoxy-6-(p-tolylsulfonyl)-β-cyclodextrin (TsO-β-CD) was synthesized by replacing one hydroxyl group among 21 hydroxyl groups in β-CD under various pH conditions using p-toluenesulfonyl chloride(p-TsCl),and used to synthesis polyrotaxane by threading TsO-β-CD on PPG-diamine with a molecular weight of 2000, followed by end capping using Trt-Gly-OH , N-Hydroxysuccinimide (NHS), ethylene dichloride (EDC). The synthesized CD derivatives and polyrotaxane were characterized by 1HNMR and FTIR spectroscopies.

关键词

Mono-6-tosyl-β -cyclodextrin, Polyrotaxane, Cyclodextrin, Tosylation

研究领域

Chemical Engineering, Bioengineering, Chemistry, Material Sciences

参考文献

1. Liu, H., Qi, C., Feng, Z. et al. Adsorption of trace thorium(IV) from aqueous solution by mono-modified β-cyclodextrin polyrotaxane using response surface methodology (RSM). J Radioanal Nucl Chem 314, 1607–1618 (2017).
2. Xu, L.; Xing, C.-Y.; Ke, D.; Chen, L.; Qiu, Z.-J.; Zeng, S.-L.; Li, B.-J.; Zhang, S. Amino-Functionalized β-Cyclodextrin to Construct Green Metal−Organic Framework Materials for CO2 Capture. ACS Appl.Mater. Interfaces 2020, 12, 3032−3041.

基金

1. the Ministry of Trade Industry & Energy (No. 20011422)

补充材料

暂无数据

附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

知识共享许可协议

Copyright © 2023 Lee et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.