PCL/graphene 3D scaffold fabrication and in vitro analysis using a solvent casting and particulate leaching assembly process

发表日期 April 28, 2023 (DOI: https://doi.org/10.54985/peeref.2304p4710615)

未经同行评议

5^th Place Peeref Competition

作者

Silvia Anitasari¹ , Ching-Zong Wu² , Yung-Kang Shen² , Yan-Sin Tsai²

1. Universitas Mulawarman
2. Taipei Medical University

会议/活动

Taiwan International Dental Show, November 2022 (Taipei, Taiwan)

海报摘要

The ideal percentage of PCL/graphene for bone cell proliferation is required; therefore, the characteristics and biodegradation of this composite must be determined prior to continuing biological exploration, such as viability testing. In the current study, a PCL/graphene scaffold with graphene concentrations of 0.5, 1.5, and 2.5 wt% has been produced using solvent casting and particulate leaching methods. Furthermore, the scaffold was cultured with osteoblast-like (MG-63) cells, and the 2.5 wt% G concentration revealed enhanced cell proliferation to other concentrations. This finding suggests that PCL/graphene scaffolds could potentially have biomedical and tissue engineering applications.

关键词

Polycaprolactone, Graphene, MG-63 cells

研究领域

Material Sciences

参考文献

1. A. Sola, J. Bertacchini, D. A’vella, L. Anselmi, T. Maraldi, S. Marmiroli, M. Messori. Mater Sci Eng. 2019, 96, 153.
2. Y. Tamada, Y. Ikada. Polymer. 1993, 34, 2208.
3. B. Feng, J, Z. Jinkang, W. Zhen, L. Jianxi, C. Jiang, L. Jian, M. Guolin, D. Xin. Biomed Mater. 2011, 6, 015007
4. S. Anitasari. CZ. Wu, YK. Shen, 2023. Bioengineering. 2023,10,305.
5. O. Guler, N. Bagci. J Mater Res Tech. 2020, 9,6808.

基金

1. Ministry of Science and Technology, Taiwan (No. No. MOST 111-2221-E-038-021)

补充材料

暂无数据

附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

知识共享许可协议

Copyright © 2023 Anitasari et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.