Mechanism of amitriptyline adsorption on Ca-montmorillonite

作者

Po-Hsiang Chang¹ , Wei-Teh Jiang¹ , Zhaohui Li² , Chung-Yih Kuo³ , Jiin-Shuh Jean¹ , Wan-Ru Chen⁴ , Guocheng Lv⁵

1. Department of Earth Sciences, National Cheng Kung University
2. Geosciences Department, University of Wisconsin – Parkside
3. Department of Public Health, Chung Shan Medical University
4. Department of Environmental Engineering, National Cheng Kung University
5. School of Materials Science and Technology, China University of Geosciences

会议/活动

The 1st International Conference on Emerging Contaminants (EMCON Forum 2013), October 2013 (Kaohsiung, Taiwan)

海报摘要

The uptake of amitriptyline (AMI) from aqueous environment by Ca-montmorillonite (SAz-2) was studied in a batch system under different physicochemical conditions. The adsorbent was characterized by X-ray diffraction and Fourier transform infrared (FTIR) analyses. The AMI adsorption on SAz-2 obeyed the Langmuir isotherm with a capacity of 330 mg/g (1.05 mmol/g) at pH 6–7. The adsorption kinetics was fast, almost reaching equilibrium in 2 h, and followed a pseudo-second-order kinetic model. Desorption of exchangeable cations correlated with the AMI adsorption well, indicating that cation exchange was the major mechanism. The higher adsorption capacity suggested that SAz-2 could be a good candidate to remove AMI from wastewater and would be an important environmental sink for the fate and transport of AMI in soils and groundwater.

关键词

Amitriptyline, Cation exchange, Intercalation, Montmorillonite, FTIR

研究领域

Environmental Engineering

参考文献

1. L.C.G. Hoegberg, T.B. Groenlykke, U. Abildtrup, H.R. Angelo, Combined paracetamol and amitriptyline adsorption to activated charcoal, Clin. Toxicol. 48 (2010) 898–903.
2. E.J.F. Franssen, P.W.A. Kunst, P.M. Bet, R. van Schijndel, A.C. van Loenen, A.J. Wilhelm, Toxicokinetics of nortriptyline and amitriptyline: Two case reports, Ther. Drug Monit. 25 (2003) 248–251.
3. T. Brodin, J. Fick, M. Jonsson, J. Klaminder, Dilute Concentrations of a Psychiatric drug alter behavior of fish from natural populations, Science 339 (2013) 814–815.
4. A.L. Green, Ionization constants and water solubilities of some aminoalkylphenothiazine tranquillizers and related compounds, J. Pharm. Pharmacol. 19 (1967) 10-16.
5. S. Bindya, W.-T. Wong, M.A. Ashok, H.S. Yathirajan, R.S. Rathore, Amitriptylinium picrate: conformational disorder, Acta Crystallogr. Sect. C-Cryst. Struct. Commun. 63 (2007) O546–O548.
6. I. Turku, T. Sainio, E. Paatero, Thermodynamics of tetracycline adsorption on silica, Environ. Chem. Lett. 5 (2007) 225–228.

基金

暂无数据

补充材料

暂无数据

附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

知识共享许可协议

Copyright © 2023 Chang et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.