Role of aspirin in the prevention of preeclampsia

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作者

Kruthica J.G¹ , Iyshwarya B K¹ , Ramakrishnan V¹

1. Chettinad Academy of Research and Education

会议/活动

International Conference on Current Trends in Biomedical Research (ICTBR), September 2022 (Chennai, India)

海报摘要

Pre-eclampsia, or toxaemia, is a potentially fatal condition characterized by extremely high blood pressure (hypertension). Women who are pregnant are more likely to suffer from hypertension disorders such as gestational hypertension. In addition to placental abruption, HELLP syndrome, fetal growth restriction, and preterm birth, pre-eclampsia can also result in organ damage such as strokes and cardiovascular disease. An individual who has a preeclamptic condition is twice as likely to suffer a heart attack or stroke later in life. The miR-200 family has been linked with preeclampsia and upregulated in preeclamptic plasma and placenta. Furthermore, aspirin suppressed the miR-200 family, and these miR-200 family-mediated cell activities, such as cell invasion and EMT alterations, were entirely reversed. The most recent clinical studies back up the use of low-dose aspirin to prevent pre-eclampsia. Prescriptions for low-dose aspirin are issued to prevent placental complications and foetal growth restriction.

关键词

Hypertension, Proteinuria, Placental abruption, Pre-term births, Aspirin

研究领域

Genetics

参考文献

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基金

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补充材料

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附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

Data sharing not applicable to this poster as no datasets were generated or analyzed during the current study.

知识共享许可协议

Copyright © 2022 J.G et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.