Wai Lo

United States UConn

期刊

评论了 Journal of the History of Collections
They are looking for Editor in Chief position. The appointment will be from January 2024 for an initial three-year term, with scope to extend subject to mutual interest. This is the position announcement: https://academic.oup.com/jhc/pages/editor-in-chief-application

论文

评论了 The Journal of Nutrition
They are looking for Editor in Chief. The Editor-in-Chief is expected to provide innovative leadership in the evolving area of scientific communication while fulfilling best publishing practices that advance the journal. The Editor-in-Chief is expected to serve in the position for an initial five-year term, with potential renewal for an additional term. This is the announcement: https://nutrition.org/publications/jn-editor-in-chief/

期刊

评论了 Cellular and Molecular Bioengineering
They are looking for an Editor-in-Chief for the journal with relevant backgrounds to the field and the vision and desire to continue the journal’s growth, maintain its reputation, and work productively with Sprinter-Nature and BMES staff. The role will serve an initial three-year term, with the potential for a second three-year term. This is their announcement: https://www.bmes.org/news/open-editor-in-chief-positions

期刊

评论了 ANNALS OF BIOMEDICAL ENGINEERING
They are looking for an Editor-in-Chief for the journal with relevant backgrounds to the field and the vision and desire to continue the journal’s growth, maintain its reputation, and work productively with Sprinter-Nature and BMES staff. The role will serve an initial three-year term, with the potential for a second three-year term. This is their announcement: https://www.bmes.org/news/open-editor-in-chief-positions

论文

评论了 The CD34+ Cell Dose Matters in Hematopoietic Stem Cell Transplantation with Sibling Donors Receiving Peripheral Blood Stem-Cells
The CD34 cell dose has impact on the outcome in sibling donor HSCT using peripheral-blood stem-cells.

论文

评论了 High-Dose Melphalan and Autologous Peripheral Blood Stem Cell Transplantation in AL Amyloidosis
Seem an interesting paper. How has the treatment of AL amyloidosis evolved over the past three decades, particularly in terms of patient eligibility, stem cell collection, and the integration of novel therapies, and what are the long-term outcomes and current challenges in managing this condition?

论文

评论了 Peripheral Blood Stem Cell Transplantation Improves Liver Functional Reserve
Very interesting! This paper assesses autologous peripheral blood stem cell transplantation in treating hepatitis B-induced liver cirrhosis. Involving 51 patients, it compares a treatment group receiving stem cell transplantation and medical treatment with a control group receiving only medical treatment. Results over 48 weeks show significant improvements in liver function and symptom relief in the treatment group, suggesting the potential effectiveness of this approach for liver cirrhosis caused by hepatitis B.

论文

评论了 Immune Reconstitution After Double Umbilical Cord Blood Stem Cell Transplantation: Comparison With Peripheral Blood Stem Cell Transplantation
This study contrasts immune recovery in umbilical cord blood (UCB) and HLA-matched unrelated donor (MUD) stem cell transplant recipients. It finds a notable delay in T cell recovery up to 6 months post-transplant in UCB patients, while their B and NK cell recovery is faster. Early high BAFF levels in UCB patients contribute to quicker B cell reconstitution, potentially reducing chronic graft-versus-host disease incidence. However, UCB recipients face increased infectious risks due to a significant T cell deficiency in the first 6 months.

研讨会

评论了 Non-academic careers for biological physicists
Non-academic career paths leverage the interdisciplinary training of biological physicists and their ability to tackle complex problems, making them well-suited for a range of industries beyond academia.

论文

评论了 The association between lipid-lowering drugs and circulating concentration of PCSK9
Lowering LDL cholesterol is essential for reducing cardiovascular disease risks, typically addressed with lifestyle changes and medications like statins. For high-risk patients who don't meet LDL targets with statins and ezetimibe, PCSK9 inhibitors have shown promise. These inhibitors are particularly effective for patients with familial hypercholesterolemia. While statins can increase PCSK9 levels and potentially diminish their effectiveness, the role of PCSK9 as a cardiovascular risk predictor remains unclear. Emerging treatments aim to inhibit PCSK9 more effectively. Further research is needed to understand the clinical significance of PCSK9 levels in cardiovascular risk assessment and treatment resistance.

论文

评论了 Association of Lipid-Lowering Drugs With Risk of Psoriasis
This study explores the connection between lipid-lowering drugs and psoriasis risk, focusing on genetically proxied inhibition of certain enzymes (HMGCR, NPC1L1, and PCSK9) using data from large genome-wide association studies. It found that inhibition of PCSK9, associated with lower LDL levels, was linked to a reduced risk of psoriasis, a finding supported by two large datasets. The study did not find a robust association for HMGCR or NPC1L1 inhibition. These results, derived from mendelian randomization, suggest PCSK9 plays a role in psoriasis pathogenesis and that its inhibition could potentially lower psoriasis risk.

论文

评论了 Ten simple rules for collaborative lesson development
Great paper, I have copied and pasted the 10 rules here Rule 1: Clarify your audience Rule 2: Make lessons modular Rule 3: Teach best practices for lesson development Rule 4: Encourage and empower contributors Rule 5: Build community around lessons Rule 6: Publish periodically and recognize contributions Rule 7: Evaluate lessons at several scales Rule 8: Reduce, reuse, recycle Rule 9: Link to other resources Rule 10: You can’t please everyone

论文

评论了 Ten simple rules for structuring papers
Great review paper for how to structure a paper, so I have copied and pasted the top 4 rules here: Rule 1: Focus your paper on a central contribution, which you communicate in the title Rule 2: Write for flesh-and-blood human beings who do not know your work Rule 3: Stick to the context-content-conclusion (C-C-C) scheme Rule 4: Optimize your logical flow by avoiding zig-zag and using parallelism

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评论了 Interdisciplinary team working in the Irish primary healthcare system: Analysis of ‘invisible’ bottom up innovations using Normalisation Process Theory
Very interesting! This paper examines alternative forms of interdisciplinary working in Irish primary care beyond the National Primary Care Strategy's framework, revealing that local, innovative, and preventive patient-centered approaches driven by diverse professional groups show positive impacts but face challenges due to economic constraints and lack of recognition by senior management.

论文

评论了 Blood Test for Breast Cancer Screening through the Detection of Tumor-Associated Circulating Transcripts
This study developed a blood test for early detection of breast cancer using mRNA-based tests, demonstrating superior sensitivity, specificity, and accuracy compared to conventional methods across various cancer stages, offering a promising tool for precision oncology.