Wai Lo

United States UConn

论文

评论了 Handwriting of perovskite optoelectronic devices on diverse substrates
By filling common ballpoint pens with inks made of various conductive materials, researchers have hand-drawn light-emitting diodes (LEDs) on paper, fabric and everyday 3D objects.

论文

评论了 Trigger hair thermoreceptors provide for heat-induced calcium-electrical excitability in Venus flytrap
Interesting article! The authors think that by triggering the trap to close, heat sensors protect the plant’s trigger hairs and allow it to continue to hunt prey throughout hot summers.

海报

评论了 Infecciones COVID-19 en Personas con Pauta de Vacunación Completa en un Hospital Secundario
It would be good if they provide a English version.

论文

评论了 Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery
The flexibility and platform nature of LNP enable efficient intracellular delivery of a variety of therapeutic nucleic acids and provide many novel treatment options for the diseases that are previously untreatable.

海报

评论了 Sustainable Mobility Public Transport for Prayagraj, Uttarpradesh
It is unclear how the proposed public transport system would promote health equity in public.

海报

评论了 System Design Planing for farm-to-table farm produce
Local and regional food systems should grow as consumers demand produce from their communities and establish stronger relationships with their local farmers and ranchers. Producers, community members, consumers, educators and many others should involve in developing functioning local food systems.

研讨会

评论了 Publishing open access in 2024
Looking forward to learn the open access trend in academic journals in 2024.

论文

评论了 Injectable and biodegradable piezoelectric hydrogel for osteoarthritis treatment
One of my latest publications in 2023 in Nature Communications. Enjoy!

论文

评论了 The era of bioengineering: how will this affect the next generation of cancer immunotherapy?
This review discusses the impact of bioengineering on cancer immunotherapy, focusing on overcoming current limitations like systemic toxicity and cost through innovative solutions like biomaterials for targeted delivery. It emphasizes the potential of bioengineering in enhancing immunotherapy efficacy and safety, suggesting a promising future for cancer treatment through advanced technological interventions.

论文

评论了 Molecular targeting in acute myeloid leukemia
How do recent advances in genomic screening and computer-assisted techniques contribute to developing new targeted therapies for acute myeloid leukemia (AML)?

论文

评论了 Chronic diseases, inflammation, and spices: how are they linked?
This review highlights that major chronic diseases, including cancer, are often induced by factors such as infections, obesity, and diet through chronic inflammation. It emphasizes the potential of dietary agents, particularly spices, in suppressing inflammatory pathways, thereby playing a crucial role in preventing and treating cancer and other chronic diseases, as evidenced by lower cancer incidence in countries with high spice consumption.

论文

评论了 The influence of diet on anti-cancer immune responsiveness
Seems interesting! The main finding of this review is that nutrition and diet, including specific dietary patterns like the Mediterranean and ketogenic diets, as well as supplements like omega-3 and polyphenols, can potentially enhance the immune response against cancer and may improve the effectiveness of anticancer immunotherapy.

论文

评论了 Immunogenic cell death in cancer: concept and therapeutic implications
Great article, Regulated cell death (RCD) varies in its molecular mechanisms and immunogenicity, with apoptosis typically being immunologically silent and necroptosis involving specific kinase activations; however, the immunogenicity of RCD cannot be solely determined by its molecular pathways. Future research in cancer immuno(therapy) should focus on identifying novel inducers of immunogenic cell death (ICD), developing strategies to enhance the immunogenicity of non-immunogenic RCD variants, and combining ICD inducers with immunotherapy for improved cancer treatment.

论文

评论了 Hypoxia and the phenomenon of immune exclusion
This research explores the complex relationship between tumor hypoxia and the effectiveness of immunotherapy in solid tumors, emphasizing the need for further studies to understand how hypoxia influences immune exclusion and to develop more effective combinational treatment strategies.

论文

评论了 SARS-CoV-2 before and after Omicron: two different viruses and two different diseases?
This review details the unique observation and analysis of the evolution, variant emergence, replication shifts, and immune evasion of SARS-CoV-2, significantly impacting its spread and the clinical outcomes of COVID-19.