Article
Reproductive Biology
Qujia Gama, Shuhan Luo, Pengfei Wu, Lulu Wang, Sijia Liu, Hongwei Zhang, Li Sun, Yiqin Wang, Min Yu, Xiaojun Chen, Weiwei Shan, Xuezhen Luo
Summary: This study investigated the efficacy of fertility-preserving treatment for young women with synchronous primary neoplasm of endometrium and ovary. The results showed that fertility-sparing treatment is feasible, but strict screening and monitoring are necessary.
JOURNAL OF OVARIAN RESEARCH
(2023)
Article
Reproductive Biology
Nedaa Mohammed Bahkali, Kholoud A. Ghamri, Leena Fayed Aladwani, Teaf Hasan Alzaydi, Farah Abdullah Aljarid, Nuha Abdullah Alamoudi, Kholoud Ali Alamri, Rahaf Ali Jifri, Ghaday Turki Alzhrani, Roba Mohammed Qurain
Summary: Women in the western region of Saudi Arabia have a lower risk of developing preeclampsia, but they have poor knowledge about the disorder. There is a need to increase awareness of preeclampsia.
INTERNATIONAL JOURNAL OF WOMENS HEALTH AND REPRODUCTION SCIENCES
(2023)
Article
Obstetrics & Gynecology
Kreete Lull, Elin Org
Summary: Studies have shown the importance of microbial communities in various parts of the human body for health. It has been recently discovered that the uterine cavity is not sterile and has its own microbiome, which affects female fertility and gynecological pathologies. However, there is currently no consensus on the sampling methods and definition of a healthy endometrial microbial profile.
SEMINARS IN REPRODUCTIVE MEDICINE
(2023)
Article
Reproductive Biology
Yanyan Wang, Jianmin Wang, Qing Li, Rong Xuan, Yanfei Guo, Peipei He, Tianle Chao
Summary: This study investigates the role of miRNAs in the ovarian tissue development during sexual maturity in goats. The results reveal the changes in miRNA and serum hormone levels in the ovaries, providing insights into the molecular regulatory mechanisms of miRNAs in ovarian tissue during sexual maturity in goats.
JOURNAL OF OVARIAN RESEARCH
(2023)
Article
Genetics & Heredity
Marta Budzinska, Marzena Kamieniczna, Lukasz Wojnar, Kamil Gill, Malgorzata Piasecka, Michal Kups, Monika Fraczek
Summary: Long-term exposure to scrotal hyperthermia can reduce sperm quality in humans, leading to oxidative stress, apoptosis, and deterioration of sperm parameters.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Genetics & Heredity
Miroslav Hornak, Katerina Bezdekova, David Kubicek, Rostislav Navratil, Veronika Hola, Maria Balcova, Magdalena Bohmova, Katerina Weisova, Katerina Vesela
Summary: PGT-M allows early diagnosis of monogenic disorders, preventing their transmission in affected families. This study describes a PGT protocol using next-generation sequencing for mutation testing, haplotyping, and aneuploidy screening.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Agriculture, Dairy & Animal Science
Zulfiqar Ahmed, Wei Liu, Jie Yu, Hong Dong, Zahid Naseer, Imtiaz Ahmad, Imran Ahmed, Xijun Wang
Summary: In this study, the miRNA expression patterns during testicular development in Dezhou donkeys were investigated. A total of 315 miRNAs displayed age-dependent expression differences, and several of them were found to be associated with male reproductive pathways in donkeys. These findings contribute to our understanding of microRNA regulation in equine fertility and spermatogenesis.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Review
Obstetrics & Gynecology
Tammy Lee, Jay Natalwala, Vincent Chapple, Yanhe Liu
Summary: With the advancement in computing power and accumulation of embryo image data, artificial intelligence (AI) has been applied in embryo selection in IVF. Machine learning (ML) has the potential to reduce subjectivity and save time, but the lack of interpretability in modern deep learning (DL) techniques has raised concerns. The effectiveness of black-box models lacks confirmation from randomized controlled trials, and recent evidence suggests underperformance compared to interpretable ML models. Interpretable AI is gaining support due to its ethical advantages and technical feasibility. A novel classification system for embryo selection models is proposed, focusing on subjectivity, interpretability, and explainability.
HUMAN REPRODUCTION
(2023)
Article
Agriculture, Dairy & Animal Science
M. Contreras Huamani, C. A. Olaguivel Flores, C. Y. Guillen Palomino, M. I. Carretero, F. G. Fumuso, I. M. Laines Arcce
Summary: The aim of this study was to evaluate the pregnancy outcomes and birth rates of alpaca females inseminated with frozen semen using two commercial extenders. The results showed that similar efficiency rates of pregnancy and alive offspring can be achieved through artificial insemination with frozen semen using Biladyl (R) B or AndroMed (R) diluents.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Review
Obstetrics & Gynecology
Yujun Liu, Yixin Ren, Hao Feng, Yuqian Wang, Liying Yan, Jie Qiao, Ping Liu
Summary: This article provides an overview of the development of PGT-M in China over the past 24 years, including the general steps, ethical considerations, and government policies. Additionally, potential techniques and strategies for the future are proposed.
Article
Endocrinology & Metabolism
Bixia Huang, Hui Li, Bin Xu, Ning Li, Xiaofei Wang, Yanping Li, Jing Zhao
Summary: This study aimed to explore the association between controlled ovarian stimulation (COS) protocols and euploid blastocyst rate in pre-implantation genetic testing for aneuploidy (PGT-A) cycles. The study included 457 PGT-A cycles and found that the GnRH-ant protocol was the most effective, with significantly higher euploidy rates compared to the PPOS protocol. This emphasizes the importance of personalized treatment strategies.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Nathalie Oulhen, Shumpei Morita, Cosmo Pieplow, Thomas M. Onorato, Stephany Foster, Gary Wessel
Summary: This study provides the first single cell RNA sequencing data sets of mature ovaries in echinoderms, elucidating the structure and functional biology of the ovary as well as aiding in the identification of stem cells for gamete production and understanding the evolution of reproduction in this phylum.
MOLECULAR REPRODUCTION AND DEVELOPMENT
(2023)
Review
Obstetrics & Gynecology
Lanlan Zhang, Zun Wang, Lingnan Kong, Huan Liu, Ziyang Ma, Miaomiao Xu, Suliya Yushanjiang, Dongzhi Yuan, Linlin Yu
Summary: This meta-analysis suggests that SGLT2 inhibitors may be a potential alternative therapy for overweight/obese women with PCOS who do not respond well to metformin treatment. Further large randomized controlled trials and cost-effectiveness analyses are needed to guide the use of SGLT2 inhibitors in this population.
REPRODUCTIVE SCIENCES
(2023)
Article
Endocrinology & Metabolism
Victoria G. Wesevich, Serin I. Seckin, Dawn A. Kelk, Amanda N. Kallen, Pinar H. Kodaman
Summary: This study investigated the impact of premature progesterone rise in IVF on pregnancy outcomes and found that the change in progesterone level and the ratio of gonadotropins play important roles in predicting pregnancy rates and optimizing clinical decision-making.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
J. C. Bond, C. M. Coleman, J. J. Yland, A. K. Wesselink, T. Wang, M. Willis, E. E. Hatch, K. J. Rothman, D. Savitz, M. L. Eisenberg, L. A. Wise
Summary: This study found that female sleep duration had little association with spontaneous abortion (SAB), while male short sleep duration, female night work, and discrepancies in work schedules among partners had modest positive associations with SAB incidence.
HUMAN REPRODUCTION
(2023)
Article
Biochemistry & Molecular Biology
Emma Whittington, Murielle Alund
MOLECULAR REPRODUCTION AND DEVELOPMENT
(2023)
Article
Plant Sciences
J. Carballo, A. Achilli, F. Hernandez, M. Bocchini, M. C. Pasten, G. Marconi, E. Albertini, D. Zappacosta, V. Echenique
Summary: This study utilized the MCSeEd technique to investigate the differences in methylation patterns in different genotypes of Eragrostis curvula. The results showed that polyploid/apomictic genotypes had more differentially methylated positions and regions than diploid sexual ones. Additionally, methylation was found to play an important role in reproductive pathways and ploidy changes.
PLANT REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Marina Paula Andres, Luiza Gama Coelho Riccio, Henrique Mendonca Abrao, Mariana Simionato Manzini, Lais Braga, Mauricio Simoes Abrao
Summary: This study evaluated the impact of pain symptoms on the quality of life in women with endometriosis using the visual analogue scale. The results showed that severe pain (VAS score >= 7 cm) significantly decreased the quality of life, while mild to moderate pain (VAS < 7 cm) resulted in better quality of life.
REPRODUCTIVE SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Bin Meng, Xiaoning Yang, Shiwei Luo, Chong Shen, Jia Qi, Haifeng Zhang, Yandong Li, Ying Xue, Juan Zhao, Pengxiang Qu, Enqi Liu
Summary: This study used proteomics analysis to construct a protein profile of the ovaries in a PCOS mouse model. The results showed significant differences in protein profile between the PCOS and control group. Differentially expressed proteins were mainly involved in lipid metabolism, oxidative stress, and immune response. This study fills the gap in PCOS ovarian proteomic data and provides an important reference for drug development and treatment of PCOS.
MOLECULAR REPRODUCTION AND DEVELOPMENT
(2023)
Review
Obstetrics & Gynecology
Jenny van Dongen, Nikki Hubers, Dorret Boomsma
Summary: The study has identified genes that contribute to the likelihood of a woman giving birth to dizygotic (DZ) twins and has shown that monozygotic (MZ) twins have a stable DNA methylation pattern in their somatic tissues. This discovery opens up new possibilities for retrospective diagnosis of MZ twins and their vanished co-twins in early pregnancy.
HUMAN REPRODUCTION
(2023)