Article
Clinical Neurology
Blaise L. Worden, David F. Tolin, Michael C. Stevens
Summary: A potential barrier to effective cognitive-behavioral therapy for patients with hoarding disorder is treatment retention and compliance. This study found that abnormal brain activity in regions related to executive functioning, such as the insula, parietal, and premotor areas, was significantly associated with treatment compliance in hoarding disorder patients.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yu Jin, Shicun Xu, Zhixian Shao, Xianyu Luo, Yinzhe Wang, Yi Yu, Yuanyuan Wang
Summary: This study utilized the XGBoost model and network analysis to identify critical factors related to depression and explore their associations. The results revealed significant positive associations between anxiety and obsessive compulsive disorder (OCD), anxiety and post-traumatic stress disorder (PTSD), social anxiety disorder (SAD) and appearance anxiety, as well as negative associations between sleep quality and anxiety, sleep quality and PTSD among individuals with childhood trauma experiences and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Letizia Squarcina, Susanna Lucini Paioni, Marcella Bellani, Maria Gloria Rossetti, Josselin Houenou, Mircea Polosan, Mary L. Phillips, Michele Wessa, Paolo Brambilla
Summary: In this study, the state of white matter structures in bipolar disorder patients was investigated using TBSS and FD analyses. The results showed diffusion abnormalities primarily located in the temporo-parietal network, while no significant differences were found in the morphological complexity of white matter structures. Individual patients showed localized significant deviations in fractal dimension values.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Meng Wang, Tingting Li, Yang Xie, Dan Zhang, Yang Qu, Shuang Zhai, Xingyue Mou, Yajuan Yang, Liwei Zou, Shuman Tao, Fangbiao Tao, Xiaoyan Wu
Summary: This study finds that clustered health risk behaviors have a significant impact on mental health among young adults, and inflammatory cytokines play a negative moderating role in this relationship.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Angelina R. Sutin, Martina Luchetti, Yannick Stephan, Amanda A. Sesker, Antonio Terracciano
Summary: The study found that having a purpose in life is associated with less subjective stress. This association is similar across different age, sex, race, ethnicity, and education backgrounds, and is not moderated by psychological distress. The findings also suggest that this association is generally consistent across different cultural contexts. Therefore, having a purpose in life may contribute to better mental and physical health by reducing subjective stress.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Sara Iannattone, Silvia Spaggiari, Daniela Di Riso, Gioia Bottesi
Summary: This study aimed to explore the psychological profiles of IU, separation anxiety symptoms, and negative affectivity in Italian young adults and compare them in terms of psychological and psychosocial characteristics.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Jonah Meyerhoff, Miranda Beltzer, Sarah Popowski, Chris J. Karr, Theresa Nguyen, Joseph J. Williams, Charles J. Krause, Harsh Kumar, Ananya Bhattacharjee, David C. Mohr, Rachel Kornfield
Summary: This study examines the effectiveness of an 8-week automated interactive text messaging intervention for depression and anxiety. The results show high engagement and usability of the intervention, with significant reductions in depression symptoms. However, reductions in anxiety symptoms were not significant. Participants suggested improvements for the intervention.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Lulu Pan, Chen Huang, Yahang Liu, Jiahuan Peng, Ruilang Lin, Yongfu Yu, Guoyou Qin
Summary: This study used quantile regression to evaluate the associations between sleep duration and depression across the entire distribution of depression severity. The findings revealed that the association between sleep duration and depression was more pronounced at higher levels of depression severity. Additionally, the association between short sleep duration and depression was stronger in females and individuals with chronic diseases.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Emma Diggins, Hein Heuvelman, Mar Pujades-Rodriguez, Allan House, David Cottrell, Cathy Brennan
Summary: Self-harm is common in young people, with girls having higher rates than boys. Gender differences in exposure to risk factors such as adverse events and problematic interpersonal relationships, emotional wellbeing, and social media use may contribute to the increased risk of self-harm in girls. Further research is needed to understand why these differences exist and develop gender-specific approaches to self-harm management.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Eun Kyoung Ahn, Kyuhyun Yoon, Ji-Eun Park
Summary: This study investigated the impact of different sleep hours on the risk of cognitive decline, taking into account morningness-eveningness types. The findings suggest that the morningness group had the lowest risk of cognitive decline within the 7-9 hour sleep duration. However, when considering sleep quality, the optimal sleep duration varied among different types.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Salome Vanwoerden, Jennifer S. Silk, Erika E. Forbes, Judith K. Morgan
Summary: This study evaluates the relationship between maternal depression history and current severity with positive affect socialization and offspring's social outcomes. The results suggest that current level of maternal depression is associated with more social problems and lower quality of best friendships in children. However, positive affect socialization is not related to maternal depression history or current levels, except for a greater likelihood of mothers joining their children in expressing positive affect. Treatment history among these mothers may explain this finding.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Xinming Xu, Chengwu Feng, Han Han, Tongtong Li, Nan Wang, Qishan Yang, Yi Guo, Xinyi Gan, Xiaohua Liu, Liang Sun, Alexandru Dregan, Geng Zong, Xiang Gao
Summary: Depressive symptoms in individuals with type 2 diabetes were found to be associated with a higher risk of cardiovascular diseases, with dose-response relationships observed between depressive symptoms and various cardiovascular outcomes. This suggests that screening for depressive symptoms could help predict cardiovascular disease outcomes in individuals with type 2 diabetes.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Luisa De Risio, Mauro Pettorruso, Rebecca Collevecchio, Barbara Collacchi, Marta Boffa, Mario Santorelli, Massimo Clerici, Giovanni Martinotti, Francesca Zoratto, Marta Borgi
Summary: Social factors play a crucial role in the development and severity of depression. Social support serves as a protective factor against depression, particularly in peripartum populations. However, stigma and discrimination have a weaker effect on depression in clinical populations and ethnic minorities.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yunling Zhong, Jinlong He, Jing Luo, Jiayu Zhao, Yu Cen, Yuqin Song, Yuhang Wu, Cen Lin, Lu Pan, Jiaming Luo
Summary: This study developed a predictive model using a machine learning algorithm to assess the risk of non-suicidal self-injurious behavior (NSSI) in Chinese adolescents more accurately. The results show that depression and anxiety are the top predictors of NSSI in adolescents. Additionally, factors such as gender, age, living arrangements, psychiatric consultation history, stress, depression, anxiety, tolerance, and emotional expression were found to be associated with the risk of NSSI in adolescents.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Barbara Tomasino, Eleonora Maggioni, Maria Chiara Piani, Carolina Bonivento, Serena D'Agostini, Matteo Balestrieri, Paolo Brambilla
Summary: Mental imagery plays an important role in cognitive and emotional processes. Individuals with anxiety disorders show faster and better processing of state/psychological stimuli. The left superior frontal gyrus is differentially activated during state/psychological imagery in anxious individuals.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Jalil Rasgado-Toledo, Sai Siddharth Duvvada, Apurva Shah, Madhura Ingalhalikar, Vinoo Alluri, Eduardo A. Garza-Villarreal
Summary: This study compared the structural and functional brain networks between patients with cocaine use disorder (CUD) and healthy controls using multimodal fusion. The findings revealed abnormal brain connectivity in CUD patients, and the multimodal fusion method provided more information about brain regions affected by cocaine abuse.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Yiming Meng, Jing Sun, Guirong Zhang
Summary: Fecal microbiota transplantation (FMT) has emerged as a promising therapy for major depressive disorder (MDD), with the goal of restoring a healthy gut microbiota to alleviate symptoms. While it has shown encouraging results, there are potential hazards and limits to consider.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Rui Li, Jiaming Tang, Yizhuo Wang, Ying Wang, Hua Yang, Hongen Wei
Summary: Restricted and repetitive behaviors (RRBs) are characteristic features of neuropsychiatric disorders. This study focused on repetitive self-grooming behavior and investigated the involvement of the Pax2 gene in its control. Through the use of Pax2 neuron-specific deletion mice, the study found that the deletion of Pax2 gene affects the expression of the Arc gene in the prefrontal cortex, leading to impaired synaptic plasticity and excitatory/inhibitory imbalance, thereby contributing to the occurrence of repetitive self-grooming behavior.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Amira Abozaid, Robert Gerlai
Summary: This study investigates associative learning in zebrafish by manipulating feeding frequency and using conditioned stimuli. The results show that zebrafish fed five times a day perform better in training and consume less food compared to those fed once a day. Chronic elevated feeding improves food consumption and enhances learning and memory performance in adult zebrafish without affecting activity levels.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Review
Clinical Neurology
Meysam Amidfar, Gholamreza Askari, Yong-Ku Kim
Summary: The discovery of biomarkers and the application of metabolomics can be useful for diagnosing and treating Alzheimer's disease and mild cognitive impairment, while investigating the relationship between nutritional behavior and Alzheimer's disease can provide preventive strategies against cognitive decline and dementia.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
