Psychiatry

Article Clinical Neurology

Early life interpersonal stress and depression: Social reward processing as a potential mediator

Esther E. Palacios-Barrios, Kunal Patel, Jamie L. Hanson

Summary: This review examines the association between early life interpersonal stress (ELIS) and depression, as well as the underlying mechanisms. The research shows that ELIS affects how youth respond to social rewards, and similar impairments in social reward processing are observed in youth with depression. The authors propose a preliminary model that suggests neurobehavioral disruptions in social reward processing as a mediating factor in the connection between ELIS and depression.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Gamma oscillations in the mPFC: A potential predictive biomarker of depression and antidepressant effects

Yong-Yu Yin, Jiao-Zhao Yan, Shi-Xin Lai, Qian-Qian Wei, Si-Rui Sun, Li-Ming Zhang, Yun-Feng Li

Summary: This study found that gamma oscillations are closely associated with depression and may serve as predictive biomarkers of depression. Chronic restraint stress and lipopolysaccharide induced significant depression-like behaviors in mice and reduced gamma oscillations in the medial prefrontal cortex. Administration of ketamine, scopolamine, or fluoxetine increased gamma oscillations and exhibited rapid-acting antidepressant effects.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Transdiagnostic cognitive biases in psychiatric disorders: A systematic review and network meta-analysis

Katie M. Lavigne, Jiaxuan Deng, Delphine Raucher-Chene, Adele Hotte-Meunier, Chloe Voyer, Lisa Sarraf, Martin Lepage, Genevieve Sauve

Summary: Psychiatric disorders are characterized by cognitive deficits and cognitive biases, which are associated with specific symptoms. While cognitive biases are present across diagnoses, their severity varies.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Associations of maternal prenatal psychological symptoms and saliva cortisol with neonatal meconium microbiota: A cross-sectional study

Nadia Deflorin, Ulrike Ehlert, Rita T. Amiel Castro

Summary: Changes in the gut microbiome of infants have been associated with maternal psychological symptoms during pregnancy. This study found that maternal prenatal depressive symptoms are associated with lower diversity of the infant's microbiome, while maternal saliva cortisol levels are linked to increased diversity and changes in specific bacterial groups. Further research is needed to understand the implications of these microbiota alterations for child health.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Association between suicidal behavior and impaired glucose metabolism in first-episode drug-naive patients with schizophrenia

Zheng Ma, Hui-Xia Zhou, Da-Chun Chen, Dong-Mei Wang, Xiang-Yang Zhang

Summary: The impaired glucose metabolism in drug-na & iuml;ve schizophrenia patients is strongly associated with suicidal behavior, suggesting that glucose metabolism abnormalities may be potential biomarkers of suicide in schizophrenia patients. Regular monitoring of glucose metabolism variables is essential for suicide prevention.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Article Clinical Neurology

Transcriptomic analyses of rats exposed to chronic mild stress: Modulation by chronic treatment with the antipsychotic drug lurasidone

Veronica Begni, Moira Marizzoni, Kerstin Camile Creutzberg, Diana Morena Silipo, Mariusz Papp, Annamaria Cattaneo, Marco Andrea Riva

Summary: Exposure to stressful experiences is a significant risk factor for mental disorders, and pharmacological interventions targeting stress-induced alterations can help restore brain function. Lurasidone, an antipsychotic drug, has been shown to normalize the impairments caused by stress exposure and could be a valuable treatment for stress-induced mental illnesses. However, the mechanisms underlying the therapeutic effects of lurasidone are not well understood. This study found that chronic lurasidone treatment counteracted some of the transcriptional changes induced by chronic mild stress exposure, providing new insights into the potential therapeutic effects of lurasidone.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2024)

Letter Clinical Neurology

'The association between gut-health promoting diet and depression: A mediation analysis'

Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet

JOURNAL OF AFFECTIVE DISORDERS (2024)

Letter Clinical Neurology

National Network of Depression Centers position statement: Insurance coverage for intravenous ketamine in treatment-resistant major depressive disorder

Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick

JOURNAL OF AFFECTIVE DISORDERS (2024)

Letter Clinical Neurology

Spilling the tea about milk tea addiction - A reply to Qu et al. (2023)

Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Beliefs about depression relate to active and avoidant coping in high-symptom adolescents

Juno B. Pinder, Isaac L. Ahuvia, Sharon Chen, Jessica L. Schleider

Summary: Adolescents who hold pessimistic beliefs about the prognosis of depression are more likely to engage in avoidance behaviors and less likely to engage in activation behaviors. These findings provide insights into the relationship between beliefs about malleability and mental health outcomes in adolescents, and suggest that addressing prognostic pessimism could be a potential treatment target for reducing depressive behaviors.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Mediation and interaction of problematic internet use in the relationship between sexual minority status and depressive symptoms: Gender-based analysis

Caiyun Zhang, Keying Wu, Wanxin Wang, Yanzhi Li, Hao Zhao, Wenjian Lai, Guangduoji Shi, Lan Guo, Li Li, Ciyong Lu

Summary: This study found that sexual minority adolescents are at a higher risk of experiencing depressive symptoms, and problematic internet use plays a mediating role with gender differences in the mediating effect. In addition, there is an interaction effect between problematic internet use and sexual minority status.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Review Clinical Neurology

Facilitators of, barriers to, and preferences for e-mental health interventions for depression and anxiety in men: Metasynthesis and recommendations

Melissa J. Opozda, Melissa Oxlad, Deborah Turnbull, Himanshu Gupta, James A. Smith, Samuel Ziesing, Murray E. Nankivell, Gary Wittert

Summary: Little is known about men's use of online mental health interventions. This study aims to synthesize qualitative literature on men's preferences, attitudes, and experiences of using such interventions and provides recommendations based on the findings.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Letter Clinical Neurology

Mid-pregnancy sleep disorders and perinatal depression

Hui-Chin Chang, Shuo-Yan Gau

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Identification of central symptoms of children depression and development of two short version of Children's Depression Inventory: Based on network analysis and machine learning

Chao Zhang, Baojuan Ye, Zhifang Guo

Summary: The central symptoms of depression in Chinese rural children were identified as sadness, self-hatred, loneliness, and self-deprecation through network analysis. The developed CDI-10-N and CDI-SC showed high AUC values, demonstrating their effectiveness in screening depression symptoms.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Endometriosis, chronic pain, anxiety, and depression: A retrospective study among 12 million women

Hormoz Nassiri Kigloo, Rayan Itani, Tina Montreuil, Ido Feferkorn, Jason Raina, Togas Tulandi, Fady Mansour, Srinivasan Krishnamurthy, Eva Suarthana

Summary: This study, based on a large database, found potential associations between endometriosis and chronic pain with anxiety and depression. It suggests that clinicians should provide proper medical management for endometriosis-related pain and offer counseling for anxiety and depression.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Review Clinical Neurology

The association between trichotillomania symptoms and emotion regulation difficulties: A systematic review and meta-analysis

Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford

Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Patterns in suicide by marital status in Hong Kong, 2002-2020: Is marriage still a protective factor against suicide?

Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip

Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

Escitalopram population pharmacokinetics and remedial strategies based on CYP2C19 phenotype

Xin Liu, Gehang Ju, Xinyi Huang, Wenyu Yang, Lulu Chen, Chao Li, Qingfeng He, Nuo Xu, Xiao Zhu, Dongsheng Ouyang

Summary: This study aimed to develop a popPK model characterizing the disposition of SCIT in the Chinese population and proposed remedial strategies for non-adherence scenarios. Significant covariates impacting SCIT exposure were identified, and recommendations for dosage adjustments in different scenarios were provided based on CYP2C19 phenotypes. The study highlighted the importance of personalized medication based on patient characteristics and the utilization of popPK repository for precision dosing.

JOURNAL OF AFFECTIVE DISORDERS (2024)

Article Clinical Neurology

The mediating role of childhood maltreatment in the association between residence migration and adolescent depression

Wancheng Zheng, Lulu Wen, Yunjian Huang, Liyuan Huang, Chuming Yan, Jianghe Chen, Miao Qu

Summary: This study reveals that residence migration may contribute to adolescent depression, and childhood maltreatment may largely mediate this process. Reducing childhood maltreatment can effectively improve the depressive symptoms of migrant adolescents.

JOURNAL OF AFFECTIVE DISORDERS (2024)