Health Policy & Services

Article Health Care Sciences & Services

Evolving Trends and Economic Burden of Benzodiazepine Use: Insights From a 10-Year Predictive Model

Andro Koren, Luciana Koren, Robert Marcec, Darko Marcinko, Robert Likic

Summary: Benzodiazepines are widely prescribed in Croatia for various conditions, but long-term use is associated with negative side effects.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Cost-Utility Model of Nirmatrelvir/Ritonavir in Brazil: Analysis of a Vaccinated Population

Ricardo R. A. Fernandes, Bruno M. Barros, Milene R. da Costa, Carlos A. S. Magliano, Bernardo R. Tura, Quenia Cristina D. Morais, Marisa Santos

Summary: The use of nirmatrelvir/ritonavir in the treatment of COVID-19 in a vaccinated population was cost-effective only for immunosuppressed individuals and people over 60 years of age, while it showed a higher cost-effectiveness ratio for other groups.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Determining the Willingness to Pay for Innovative Oncology Medicines in Malaysia

Mohd Redhuan Dzulkipli, Asrul Akmal Shafie, Siti Noorsuriani Maon, Azuana Ramli, Abdul Haniff Mohammad Yahaya, See Wan Ho, Nor Ilham Ainaa Muhsin, Azmi Nor Mohd Farez Ahmat

Summary: This study aimed to determine the willingness to pay (WTP) for innovative oncology medicines among Malaysians. The results showed that more than half of the respondents were willing to pay for innovative oncology medicines, indicating the potential for collaborative funding mechanisms and appropriate financial screening to expedite access to these medicines in Malaysia.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

The Economic Burden of Biological Drugs in Rheumatoid Arthritis Treatment

Dominik Grega, Jozef Kolar

Summary: This study aimed to compare the direct (biological drugs only) and indirect (productivity loss) costs in patients with rheumatoid arthritis during the study period. The results showed that the indirect costs were 2.5 to 3 times lower than the costs of biological and targeted treatment.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Automated Peritoneal Dialysis With Remote Patient Monitoring: Clinical Effects and Economic Consequences for Poland

Joanna Augustynska, Monika Lichodziejewska-Niemierko, Beata Naumnik, Michal Seweryn, Agnieszka Leszczynska, Ryszard Gellert, Bengt Lindholm, Jacek Lange, Justyna Kopel

Summary: This study reviewed recent scientific research on the use of remote patient monitoring (RPM) in patients treated with automated peritoneal dialysis (APD), and assessed the clinical implications and potential economic value of introducing such a system into practice in Poland based on extracted relevant data. The results showed that APD with RPM significantly reduced hospitalization frequency and length, as well as APD technique failure and death.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Policy & Services

The promise of POSIT: Real-world application of the Paediatric Oncology System Integration Tool

Laura Carson, Kadia Petricca, Avram Denburg

Summary: Childhood cancer presents challenges for patients, families, communities, and health systems. There are significant disparities in outcomes between low-and middle-income countries and high-income countries. The Paediatric Oncology System Integration Tool (POSIT) has been developed as a comprehensive framework for evaluating childhood cancer systems and exploring various factors related to childhood cancer. It provides a constructive approach for improving childhood cancer outcomes.

JOURNAL OF CANCER POLICY (2024)

Article Health Care Sciences & Services

Research-to-policy Partnerships for Evidence-Informed Resource Allocation in Health Systems in Africa: An Example Using the Thanzi Programme

Juliet Nabyonga-Orem, Edward Kataika, Alexandra Rollinger, Helen Weatherly

Summary: The Thanzi Programme is a research-and-policy partnership framework that supports evidence-informed health resource allocation decisions in Africa. It achieves this through providing health economics training, strengthening partnerships between in-country and international researchers, and institutionalizing platforms at national and regional levels. It also enhances the contribution of health economics evidence in policy processes through the establishment of Health Economics and Policy Units and the Health Economics Community of Practice.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Exploring the Evolution of Statin Pricing in Australia: Observations of Price Disclosure Effects on Pharmaceutical Benefits Scheme Expenditure

Leonard Lee, Hansoo Kim

Summary: This study investigates the impact of price control measures on statin prices and government expenditure in Australia. The results show that statin prices decreased under price control measures, leading to a reduction in government expenditure. The effects of price disclosure on market share suggest that industry-prompted price reductions may be driven by market share loss.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Experiences and perceptions of continuous deep sedation: An interview study among Dutch patients and relatives

Louise Annemoon Jonker, Madelon T. Heijltjes, Judith A. C. Rietjens, Agnes van der Heide, Geeske Hendriksen, Johannes J. M. van Delden, Ghislaine J. M. W. van Thiel

Summary: This study explores the perceptions and experiences of patients and relatives regarding Continuous Deep Sedation (CDS). The findings suggest that patients and relatives consider CDS as a regular palliative care option and prioritize avoiding suffering at the end of life. They also claim a substantial say in the decision-making process.

HEALTH EXPECTATIONS (2024)

Article Economics

The labour market returns to sleep

Joan Costa-Font, Sarah Fleche, Ricardo Pagan

Summary: This study uses longitudinal data from Germany and finds that a one-hour increase in weekly sleep is associated with a rise in employment and an increase in weekly earnings. The effect on earnings comes from productivity improvements due to a decrease in working hours with longer sleep duration. The study also identifies improved mental well-being as a key mechanism driving these effects.

JOURNAL OF HEALTH ECONOMICS (2024)

Article Health Care Sciences & Services

Decision-Utility Analysis of Empiric Treatment Versus Test and Treat Strategies for Helicobacter pylori in Patients With Duodenal Ulcer

Majid Alsaha Fi, Mahmoud Mosli, Saad Alkhowaiter, Fergal Donnellan

Summary: This study compares the utility and ulcer recurrence rate of empiric treatment strategy and test and treat strategy in patients with uncomplicated duodenal ulcer. The results show that the empiric treatment strategy, within a specific range of test sensitivity, can lower the recurrence rate and result in higher quality-adjusted life-year (QALY) compared to the test and treat strategy.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

The Checklist for Standard Methodological Requirements and Reporting of Economic Evaluation of Medicines in Slovakia

Maria Bucek Psenkova, Lucia Hlavinkova, Martin Visnansky, Dominik Grega, Martina Ondrusova

Summary: This study developed a scientifically grounded checklist for economic evaluation (EE) of medicines in the Slovak health technology assessment process. The checklist was validated through an online survey and consists of 55 recommendations. Implementation of the checklist can help improve the appropriateness and standardization of EE in Slovakia.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Breast Cancer Screening in Georgia: Choosing the Most Optimal and Cost-Effective Strategy

Abyan Irzaldy, Rema Gvamichava, Tina Beruchashvili, Lela Sturua, Nicolien T. van Ravesteyn, Harry J. de Koning, Eveline A. M. Heijnsdijk

Summary: This study used the MISCAN-Breast model to evaluate 736 breast cancer mammography screening strategies. The results showed that strategies combining mammography and clinical breast examination (CBE) had higher costs and minimal differences in outcomes compared to mammography-only strategies. The current strategy in Georgia, biennial mammography screening from 40 to 70 years with CBE, is close to the optimal strategy but requires high additional costs. The optimal strategy for Georgia would be triennial mammography-only screening from 45 to 66 years.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Adapting Economic Evaluation Methods to Shifting Global Health Priorities: Assessing the Value of Health System Inputs

Finn McGuire, Sakshi Mohan, Simon Walker, Juliet Nabyonga-Orem, Freddie Ssengooba, Edward Kataika, Paul Revill

Summary: Undertaking value assessments for health system inputs is crucial for allocative efficiency, especially in low- and middle-income countries. However, there are methodological challenges in applying current economic evaluation techniques to health system input investments. A comprehensive standardized framework for value assessments does not exist, and the literature largely ignores these methodological issues, potentially leading to inaccurate cost-effectiveness assessments.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Health System Financing and Resource Allocation in Humanitarian Settings: Toward a Collaborative Policy Research Agenda in the Eastern Mediterranean Region

Sumit Mazumdar, Rana Hajjeh, Rick Brennan, Awad Mataria

Summary: This article discusses the important policy questions regarding health system financing in humanitarian settings, focusing on the Eastern Mediterranean region. The article explores the key financing functions in different challenges and suggests potential policy options. It also emphasizes the importance of collaborative research to inform policy choices aligned with universal health coverage in challenging contexts.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Health Care Sciences & Services

Study of the Direct Costs of Asthma at a Healthcare Service Provider in Bogota, Colombia

Yaneth Gil-Rojas, Pieralessandro Lasalvia, Victor Saenz, Oscar Virgueez, Maria P. Pena, Camilo Castaneda-Cardona, Maria E. Laucho-Contreras, Andres L. Gonzalez, Carmen Y. Garcia-Nuncira, Diego Rosselli

Summary: This study aimed to describe the clinical characteristics and direct medical costs associated with asthma treatment in Colombia patients. The results showed that medication use and outpatient visits were the main drivers of costs, and costs were higher in severe cases and in the adult/elderly population.

VALUE IN HEALTH REGIONAL ISSUES (2024)

Article Economics

Reminder design and childhood vaccination coverage

Jonas Cuzulan Hirani, Miriam Wust

Summary: The use of reminders in public vaccination programs can effectively increase childhood vaccination coverage, especially when sent close to the recommended vaccination age. Both digital and postal reminders have equal impact on vaccination rates. Prospective reminders can improve timely vaccinations in later childhood and help achieve high coverage for new vaccines in complex vaccination programs. Reminders prompt additional preventive care for the focal children, but have no spillover effects on other health behaviors or relatives.

JOURNAL OF HEALTH ECONOMICS (2024)

Article Economics

Unmet need in major depressive disorder and acute suicidal ideation or behavior: findings from a longitudinal electronic health record data analysis

Cheryl Neslusan, Yen-Wen Chen, Mohit Sharma, Jennifer Voelker

Summary: Using a national electronic health records database, this study examines the treatments, depression severity, and health care resource utilization among patients with major depressive disorder and acute suicidal ideation or behavior in the United States. The findings suggest a need for improved outcomes and strategies to optimize screening and treatment for this vulnerable population.

JOURNAL OF MEDICAL ECONOMICS (2023)

Article Economics

Ten-year cost-consequence analysis of weight loss on obesity-related outcomes in privately insured adults with obesity in Saudi Arabia

Hussain A. Al-Omar, Nasser Aljehani, Ali Alshehri, Abdullah Al-Khenizan, Faisal Al-Shammari, Abdulmohsen Abanumay, Volker Schnecke, Joao L. Carapinha, Saleh A. Alqhatani

Summary: This study aimed to estimate the 10-year cost-consequence of weight loss on obesity-related outcomes in a sample of privately insured adults with obesity in Saudi Arabia (KSA). The findings showed that moderate weight loss of 5-15% over 10 years is associated with substantial cost savings, and prevented incidence cases of obesity-related outcomes. This could help policymakers implement weight loss programs in KSA.

JOURNAL OF MEDICAL ECONOMICS (2023)

Article Economics

Identification of cancer chemotherapy regimens and patient cohorts in administrative claims: challenges, opportunities, and a proposed algorithm

Catherine M. Lockhart, Cara L. McDermott, Aaron B. Mendelsohn, James Marshall, Ali McBride, Gary Yee, Minghui Sam Li, Aziza Jamal-Allial, Djeneba Audrey Djibo, Gabriela Vazquez Benitez, Terese A. DeFor, Pamala A. Pawloski

Summary: This study developed an algorithm based on claims data to identify cancer patients and chemotherapy regimens for a comparative effectiveness analysis of G-CSF use. The initial algorithm underestimated the number of patients receiving chemotherapy, but by modifying the criteria, the final algorithm successfully identified 886 patients who received G-CSF.

JOURNAL OF MEDICAL ECONOMICS (2023)