Article
Chemistry, Analytical
Lixin Ma, Qian Xu, Limei Yin, Wei Wu, En Han, Chen Wang, Ruiyun Zhou, Junwen Bai, Jianrong Cai
Summary: In this study, simultaneous detection of acetamiprid and carbendazim in complex sample matrix was achieved using specific Raman tag molecules and aptamer-based nanoparticles. The method showed good resistance to spectral interference and easy separation, making it a promising approach for on-site detection of hazardous substances in food safety.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yunshan Zhang, Shijie Xu, Jian Chen, Lanyue Wang, Lina Bian, Jing Ye, Lin Weng, Xiaoyu Zhao, Cheng-Te Lin, Shuang Li, Diming Zhang
Summary: Single nucleotide polymorphisms (SNPs) are important biomarkers for disease diagnosis and prognosis. However, detecting SNPs with high specificity and sensitivity for DNA with single-base difference is challenging. This study proposes a strategy for ultrasensitive SNP detection using flap endonuclease 1 (FEN 1) manipulated semi-DNA walker reaction and catalytic hairpin assembly (CHA)-FRET loop. The strategy demonstrated superior performance for ultrasensitive detection of mutant KRAS gene and could be applied to monitor gene expression in cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yu-Ching Huang, Sheng-Fan Wang, Bo-Cheng Chen, Zih-Syuan Yang, Meng-Chi Li, Xun-Ying Wu, Meng-Jey Youh, Hui-Yun Chou, Yu-Xen Lin, Wanchai Assavalapsakul, Arunee Thitithanyanont, Li-Chen Su
Summary: In this study, a intensity-based SPR sensor using NIR-OPD was introduced for rapid and accurate detection of H5N1 avian influenza virus. The sensor exhibited high sensitivity with a detection limit of 4.3 x 104 copies/mL, which was 37 times higher than a commercial lateral flow test kit. The integration of NIR-OPD into the sensor provided advantages in compactness and cost-effectiveness, making it a promising tool for on-site detection of H5N1 AIV.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Guoqing Feng, Siqing Wang, Shihan Wang, Pengcheng Wang, Chuntao Wang, Yongxin Song, Jingkun Xiao, Chengwen Song
Summary: In this study, quantum dots (QDs)-sensitized few-layer Ti3C2Tx was successfully applied to NO2 sensing, showing a strong response, ideal selectivity, and a low detection limit. A novel dynamic gas-sensing mechanism was proposed to explain the enhancement of sensing performance by sensitization mechanisms. These findings not only demonstrate the potential of MXene in sensing applications, but also provide a theoretical perspective for designing trace-level NO2 sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Bo Peng, Xiaoxue Liu, Yao Yao, Jianfeng Ping, Yibin Ying
Summary: This study proposed wearable electrodes for real-time monitoring of leaf capacitance, which showed good flexibility and stability. The capacitance value was found to be positively correlated with leaf moisture content and showed higher value at night compared to daytime. The growth and physiological parameters of the plant were not significantly affected during capacitance monitoring using the wearable electrodes. These results demonstrate the potential of wearable electrodes for real-time and precise monitoring of plant physiological information in the future.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Xinyu Liu, Xiaoming Su, Mingyang Chen, Yangcenzi Xie, Ming Li
Summary: Rapid early diagnosis of Alzheimer's disease is crucial, but challenging. In this study, a self-calibrating biosensor based on SERS-LFIA technique is developed for accurate AD diagnosis. It has high sensitivity, excellent anti-interference capability, lowcost and easy operation.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Xiaole Han, Hongyan Yu, Li Zhang, Zhi Weng, Ling Dai, Li Wang, Lin Song, Zhongzhong Wang, Rong Zhao, Luojia Wang, Weitao Wang, Dan Bai, Yongcan Guo, Ke Lv, Guoming Xie
Summary: This study proposes a movable toehold principle to suppress leakage and accelerate catalytic reactions. The catalytic hairpin assembly with movable toehold exhibits a good signal-to-background ratio, robustness, and specificity, and demonstrates satisfactory performance in complex circuits.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Shunsuke Rokutani, Kentaro Hiraka, Hiroshi Saitoh, Taiki Saito, Yoshihiko Nonaka, Kinuko Ueno, Kaori Tsukakoshi, Noriyuki Ohnishi, Kazunori Ikebukuro
Summary: In this study, a DNA aptamer-based thermo-responsive magnetic particle (TM) assay was developed as a simple and sensitive protein detection system. The research demonstrated that the modification of aptamers on TM successfully controlled the aggregation behavior and enabled the detection of target proteins. By using capturable aptamers, the sensitivity and limit of detection of the TM assay were improved.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Bharat Sharma, K. Karuppasamy, Ashok Kumar Srivastava, Akram Alfantazi, Ashutosh Sharma
Summary: In this study, boron nitride nanotubes (BNNTs) decorated PtO2 nanoparticles (NPs) were used to form a heterojunction for enhancing the room temperature gas sensing towards dry NH3 gas. The integration of PtO2 NPs onto BNNTs provides a synergistic effect, enabling enhanced NH3 sensing capabilities with low detection limit and short response time, as well as good resistance against humidity and long-term stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Shivangi Srivastava, Ajeet Singh, Mohammad A. Sahz, Bal Chandra Yadav, Narendra Kumar Pandey
Summary: A room temperature operated V2O5 nanorods-decorated graphene oxide (GO) nanosheets-nanocomposite chemiresistor has been developed for detecting low-trace of toluene. The sensor shows high response and rapid response and recovery time, as well as good selectivity and stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Runhui Zhang, Qing Tang, Hanren Chen, Jieqi Deng, Yongyin Li, Lihong Liu
Summary: In this study, a strategy for detecting hepatocellular cancer biomarkers was developed. This strategy involved the coupling of a 6-carboxyfluorescein labelled aptamer, reduced graphene oxide, DNase I-assisted recycling amplification, and microfluidic electrokinetic stacking chip. The method demonstrated high sensitivity and specificity in detecting multiple biomarkers simultaneously, and was successfully applied to clinical serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Hongtao Feng, Siyi Min, Yuqing Huang, Zhuofei Gan, Chuwei Liang, Wen -Di Li, Yan Chen
Summary: This study presents a novel concentric gradient nanoplasmonic sensor for sensitive and label-free quantification of tumor-derived extracellular vesicles (EVs). By functionalizing the sensor with smaller aptamers, a more sensitive area is reserved for EV surface proteins, enabling the dynamic binding of EVs. The sensor exhibits high sensitivity in detecting EV binding and shows great potential for diagnosing cancer patients.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yoonseung Lee, Youngbo Choi, Surin Hong
Summary: Surface plasmon resonance imaging (SPRi) is a widely-used technology in various fields, but it faces sensitivity limitations when handling low-molecular-mass materials. This study developed an SPRi signal conversion process to enhance image contrast and convert it into quantitatively analyzed signals.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
