Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Hongkun Li, Qianqian Cai, Yali Xue, Guifen Jie
Summary: A unique dual-mode biosensor based on hydrogen-bonded organic frameworks (HOF-101) was constructed for ultrasensitive detection and imaging of oxytetracycline (OXY), using polydopamine nanoparticles (PDAs) as quencher. PDAs, with good biocompatibility and light absorption ability, were introduced onto the surface of HOF-101 to quench its electro-chemiluminescence (ECL) and photoelectrochemical (PEC) signals, achieving ultrasensitive detection of OXY.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Zhe Liu, Xichao Mo, Shuhao Tian, Jie Chen, Yanpeng Liu, Haiyang Wu, Yawei Zhao, Yanrong Wang, Shanglong Peng
Summary: This study demonstrates the fabrication of Co3O4/MX7.5 heterojunction using electrostatic adsorption and calcination strategies, and shows its potential for detecting ethanol at a relatively low temperature with long-term stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Solaleh Ghateii, Amir Jahanshahi
Summary: Recent advances in microfluidic paper-based analytical devices have shown great potential for point-of-care testing, particularly for monitoring glucose levels in diabetes patients. However, the practical application of smartphone-coupled devices has been hindered by variability in ambient lighting conditions. In this study, a machine learning-based algorithm and flash/no-flash technic were developed to address the issue, resulting in accurate monitoring of plasma glucose levels across a wide range and in various lighting conditions.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yue Wu, Rui Liu, Zediao Huang, Hengye Chen, Xiangyu Zhao, Yanmin Rao, Rongxian Bai, Wanjun Long, Jian Yang, Wei Lan, Haiyan Fu
Summary: In this study, a dual-channel colorimetric sensor was constructed to identify the authenticity and origin of Atractylodis Macrocephalae Rhizoma (AMR) using metal ions mediated color transformation of gold nanoparticles (AuNPs). The sensor accurately classified AMR samples from different origins and their counterfeits based on significantly different color transformations.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Xiaojie Qin, Binqi Wei, Yuanhang Xiang, Hao Lu, Fengfei Liu, Xinchun Li, Fan Yang
Summary: This study utilizes the coordination between exosomes and metal-organic frameworks to develop an ultrasensitive detection method for tumor-derived exosomes. The method is highly specific and fast, allowing for the profiling of different cancer types and accurate diagnosis in a clinical setting. This strategy provides new opportunities for functional materials assembly and precision diagnostics.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Shikha Shrivastava, Debashrita Mahana, Simran Nehra, Sunil Gangwar, Sandeep Singh, C. S. Yadav, Senthil Kumar Muthusamy, Anjana Dogra
Summary: In this study, the perovskite Barium Stannate (BaSnO3) thin films were investigated for CO gas sensing application. The electrical properties and gas sensing response of BaSnO3 thin films were improved by reducing the film thickness. The 90 nm thick film exhibited a higher gas sensing response at a lower temperature due to the presence of numerous grains and grain boundaries facilitating the adsorption and desorption of oxygen species.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Xuelin Zhang, Hui Dong, Hui Zhou, Yueyuan Li, Qing Liu, Hongyou Cui, Shujun Wang, Yueyun Li, Qin Wei
Summary: By regulating the surface motifs of metal nano-clusters (MNCs) based on aggregation-induced emission (AIE) strategy, a highly efficient luminescent probe AuAg NCs was designed. The introduction of Ag(I) resulted in denser surface patterns, reducing the non-radiative energy dissipation. Additionally, the spontaneous catalytic cycle amplification strategy improved the electrochemiluminescence (ECL) efficiency of AuAg NCs. The biosensor showed a wide linear relationship range and low detection limit using cardiac troponin I as a model.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feihu Li, Junjie Jing, Jinkun Li, Shuni Li, Siyu Ye, Xinru Song, Zili Zhan, Yeguang Zhang
Summary: In this study, ZnO-SnO2 heterojunction three-dimensional inverse opal photonic crystal balls (IOPB) were fabricated via rapid and liquid waste-free spray drying. The IOPBs showed higher response and faster response/recovery times compared to pure SnO2 sensors, as well as good selectivity and long-term stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yu Jin Park, Dong-Yeon Song, Dong-Myung Kim
Summary: Advancing expeditious and highly responsive in vitro diagnostic techniques is crucial for ensuring the effectiveness of disease prevention and control measures. This study utilizes the translational machinery to transform target nucleic acids into easily quantifiable proteins, offering a versatile pathway for adaptable and cost-effective nucleic acid testing.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yukun Wang, Guoming Ma, Dan Gao, Yuan Wang, Yangyang Xie, Xunbo Gao, Houxian Du, Junting Ji
Summary: This paper proposed a methane sensor based on the evanescent field of the non-adiabatic tapered optical fiber (NATOF) for high-sensitivity in-situ detection of transformer oil-dissolved methane. The sensor exhibited a detection sensitivity of 9.8 pm/ppm and a detection limit of 2.35 ppm, with excellent reversibility validated through cyclic experiments.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ruimei Zhang, Yuxin Guo, Jiawei Huang, Hongchang Li, Ruizhi Wen, Wenlei Wang
Summary: This study established a rapid method for the detection of tetracycline (TC) by utilizing sodium alginate-protected gold nanoclusters (SA-AuNCs) and europium ions (Eu3+). The proposed method showed a linear relationship over a wide range of TC concentrations, with a low detection limit and high recovery rates. Additionally, color information extracted from fluorescence images taken with a smartphone was analyzed using MATLAB, enabling semi-quantitative detection of TC in real samples without the need for time-consuming pretreatment or expensive instruments.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Review
Chemistry, Analytical
Baptiste Moeglen Paget, Keertana Vinod Ram, Shuyan Zhang, Jayakumar Perumal, Sylvain Vedraine, Georges Humbert, Malini Olivo, U. S. Dinish
Summary: Photonic crystal fibers (PCFs) have unique light-guiding properties and have been widely studied for biomedical applications. PCF-based fluorescence sensors offer highly sensitive detection of biomolecules at low sample volumes. This review discusses recent advancements in fluorescence detection using different PCF configurations and compares them with conventional fluorescence methods. Prospective applications of PCF-based fluorescence sensing and their potential use as optofluidic biopsy needles for clinically relevant biomarker detection are also discussed.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Quan Zou, Toshio Itoh, Woosuck Shin, Makoto Sawano
Summary: This study tests the classification performance of a sensing system using simulated VOC gases and finds that the AIST sensors have better sensing ability than commercial sensors. An artificial neural network is developed to predict gas concentration with excellent performance. This study provides a promising method for rapidly screening respiratory diseases.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ding Jiang, Jinghan Jiang, Xiaojiao Du, Xueling Shan, Wenchang Wang, Hiroshi Shiigi, Zhidong Chen
Summary: In this study, a self-powered photoelectrochemical sensing platform was developed for sensitive detection of tetra-cycline (TC). The platform combined sulfur-vacancy engineered CdS nanorod arrays with Ce-metal-organic frameworks to enhance the photocurrent and facilitate electron transfer. The sensing system based on this platform showed linear detection of TC and demonstrated good anti-interference ability and stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
