Electrochemistry

Article Chemistry, Analytical

Electroconductive silver nanoparticle composite films for sensing ammonia in the presence of water vapor

Madhuka V. Liyanage, Robert A. Latour, George Chumanov

Summary: Nanocomposite films containing silver nanoparticles separated by thin polymer layers were fabricated using different methods. The films exhibited changes in electrical conductivity when exposed to moist ammonia and water vapors. The conductivity changes were attributed to hydrogen bonding and direct adsorption. Drop casting method on nylon filter membranes resulted in the most reproducible films. The films with polyvinylpyrrolidone polymer layers showed a low limit of detection for ammonia in the presence of interfering water vapor. The films could be developed as ammonia sensors for environmental and biomedical applications.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Lab on a single fiber: A three-parameter sensor based on triple-SPR for one-to-one detection of DNA, pH and temperature

Pengqi Gong, Xuegang Li, Qiming Zhao, Xue Zhou, Yanan Zhang, Yong Zhao

Summary: In this paper, a multiparameter DNA hybridization sensor with temperature and pH detection channels based on a fiber-based triple surface plasmon resonance (Triple-SPR) effect is demonstrated. The innovation of this paper lies in the independent temperature and pH testing channels implemented based on a single fiber optic structure, and the high sensitivity DNA hybridization detection channel. Polydimethylsiloxane and self-assembled materials are used for the real-time detection of temperature and pH. After the modification of probe DNA, the selective detection of complementary DNA is achieved. The advantages of multi-parameter independent detection, high sensitivity, and fast response of the fiber-based Triple-SPR sensing technology are of great significance in future multi-parameter sensing, compensated detection, and real-time bio-monitoring applications.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Flexible parallel-type capacitive humidity sensors based on the composite of polyimide aerogel and graphene oxide with capability of detecting water content both in air and liquid

Kaiyue Han, Yang Li

Summary: In this study, a self-standing high performance flexible capacitive humidity sensor was developed using a composite of polyimide aerogel and graphene oxide. The sensor demonstrated high sensitivity and stability, and could monitor respiration and finger movement while also detecting water content in liquids.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Tris(2-carboxyethyl)phosphine-mediated immobilization of thiolated DNA on gold nanoclusters and its application in multiplex microRNA detection

Weidong Qin, Junhua Wang, Zhanqiu Tang, Hongyuan Tian, Zhenglong Wu

Summary: Researchers have discovered a rapid and efficient method for immobilizing DNA on gold nanoclusters (AuNCs) using tris(2carboxyethyl)phosphine (TCEP). They have also successfully fabricated a core-shell-satellite nanocomposite for simultaneous detection of microRNA-21 and microRNA-141.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Construction of the fiber optic LSPR sensor for highly sensitive detection of miR-103 by a dual signal enhancement strategy based on the hot-spot effect and HexSG4 catalysis

Wei Zhang, Hong Lei, Jiachong Li, Xiaoyan Wang, Hui Yan

Summary: In this study, we proposed a dual signal enhancement strategy for the highly sensitive detection of microRNAs using a fiber optic localized surface plasmon resonance sensor. The method involved the construction of a multimer structure and catalytic amplification to capture and detect miR-103. The sensor demonstrated high specificity, repeatability, and reproducibility, and was successfully validated with real samples.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Stable light-emitting bionic antibody-conjugated covalent organic frameworks for the adsorption of urea and control of ethyl carbamate

Chen Meng, Yunhai Chen, Dianwei Zhang, Huilin Liu, Baoguo Sun

Summary: In this study, a novel COFs(azide)@BAs material was prepared for the adsorption of urea and indirect control of EC in Huangjiu processing. The material exhibited a low detection limit for urea and satisfactory removal efficiency for EC, showing great potential for application in food safety control.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Improved selectivity of borophene sensor towards NO2 gas with PEI-ZIF-8 overlayer

Naveen Kumar Arkoti, Kaushik Pal

Summary: Stable and selective gas sensing is crucial for detecting toxic gases and preventing gas leak accidents. In this study, borophene is identified as a potential material for NO2 gas sensing, while a polyetherimide-zeolitic imidazole framework mixed matrix membrane is used as a selective gas separation membrane. Experimental results demonstrate that the fabricated sensors exhibit stable and reliable detection performance for NO2 gas at varying concentrations.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Highly sensitive Ti3C2Tx MXenes-RGO humidity sensor for human non-contact respiratory monitoring

Shuguo Yu, Chu Chen, Peng Li, Hongyan Zhang, Haiyang Zhang

Summary: A highly sensitive and stable Ti3C2Tx MXenes-RGO humidity sensor was developed for real-time respiratory monitoring. The sensor exhibits high sensitivity, low humidity hysteresis, short response/recovery time, and good stability and repeatability.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Confinement of gold nanoclusters on hydroxy double salt for versatile fluorescent sensing of bio-enzymes

Mengke Wang, Yaqing Han, Rui Huang, Zhonghao Wang, Guannan Wang

Summary: The confinement effect of AuNCs@HDS significantly improves the fluorescence properties of AuNCs and enables versatile fluorescent sensing strategy for bio-enzymes.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

An electrochemical metallic nanowire aptasensor for rapid and ultrasensitive detection of cardiac troponin I

Junfeng Zhang, Kai Sun, Jiangtao Ren, Han Wang, Jing Cheng

Summary: A metallic nanowire aptasensor with high sensitivity and short detection time was developed for the early diagnosis and prognostic monitoring of heart failure by detecting cardiac troponin I (cTnI). The sensor exhibited excellent detection performance, including high sensitivity, short detection time, high specificity, and good reproducibility, making it a potential application in portable devices for continuous monitoring of cardiomyocyte injury.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Fluorescent probes based on quinoline and naphthidine derivatives with NIR and AIE properties for real-time monitoring mitochondrial viscosity during mitophagy

Jing-Yu Zhao, Gang Zhang, Hao-Chi Hao, Ru Sun, Yu-Jie Xu, Jian-Feng Ge

Summary: This study presents the discovery of mitochondria probes for real-time monitoring of mitophagy process. The probes showed excellent fluorescence performance and targeting capability, and were able to detect changes in mitochondrial viscosity. These probes have significant potential for investigating dynamic pathological processes related to mitophagy.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Ion-selective organic electrochemical transistors for the determination of potassium in clinical samples

Marc Clua Estivill, Adil Ait Yazza, Pascal Blondeau, Francisco J. Andrade

Summary: This study presents the development and optimization of a paper-based ion-selective organic electrochemical transistor (IS-OECT) with remarkable analytical performance. The device combines thick-film transistor technology, optimal ion-selective membrane composition and thickness to achieve high sensitivities and good selectivity for detecting potassium concentrations in blood.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Label-free identification of DNA single-base mutation for clinical diagnostics based on plasmonic SiNW@AgNP arrays

Han Lu, Dan Wang, Guangfei Huang, Qilin Ma, Yuan Zhang, Mingliang Jin, Lingling Shui

Summary: Surface-enhanced Raman spectroscopy (SERS) has great potential in DNA analysis, but the identification of single-base mutations is still limited. In this work, plasmonic SiNW arrays decorated with Ag nanoparticles (SiNW@AgNP arrays) were developed to address these challenges, showing excellent sensitivity and reproducibility. Under optimized conditions, SiNW@AgNP arrays enable the detection of DNA bases and the discrimination of gene mutations.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Biophysics

Plasmonic digital PCR for discriminative detection of SARS-CoV-2 variants

Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon

Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.

BIOSENSORS & BIOELECTRONICS (2024)

Article Chemistry, Analytical

Development of integrated optical biosensors based on low-cost stereolithography fabrication and multispectral signature for Lab-On-Chip applications

Gianni Antonelli, Arianna Mencattini, Micol Massimiani, Valentina Lacconi, Joanna Filippi, Margherita Losardo, Michele 'Orazio, Paola Casti, Mario Bragaglia, Giorgia Curci, Francesca Nanni, Luisa Campagnolo, Eugenio Martinelli

Summary: Lab-On-Chips (LOCs) offer advantages in studying biological models and evaluating drug efficacy. This research presents a cost-effective technique to integrate optical biosensors into the lab-on-chip and successfully measures pH in human embryonic stem cell cultures, advancing the understanding of cell-scale metabolic mechanisms.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

DNA walker-powered SERS logic aptasensors for accurate imaging and identification of tumor cells

Chen Dong, Jingrong Xiong, Yeran Wang, Jing Liang, Chenlong Yan, Huiming Lv, Jingjing Zhang, Chunyuan Song, Lianhui Wang

Summary: In this study, a DNA walker-powered SERS logic aptasensor was proposed for accurate identification of tumor cells. The aptasensor can sensitively and specifically image membrane proteins on single live cells, enabling logical analysis for cancer cell classification and subtypes.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Nanocasting technique for imprinting a natural leaf pattern on biomimetic polyaniline to yield an artificial hierarchical surface structure for gas sensing

Kun-Hao Luo, Yu-Han Hung, Aamna Bibi, Yi-Min Li, Chuan Hu, Jui-Ming Yeh

Summary: This study focuses on the synthesis and utilization of a novel biomimetic material, Bio-PANI, for H2S gas sensing applications. The Bio-PANI coating exhibits a larger specific surface area and better electrochemical performances compared to conventional PANI coating. The Bio-PANI-coated sensor shows higher response and better stability.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Enhanced performance of electro-responsive PVC gel actuators prepared by advanced rapid thermal melting technique

Yuwei Wu, Min Yu, Chengbo Tian, David Vokoun, Runqi Hu, Hengzao Ge, Hao Zhang, Ivo Stachiv

Summary: This study proposes a new method for fabricating PVC gel using a thermal melting approach, which significantly improves its actuation performance while reducing fabrication time and cost.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

An APE1-mediated isothermal target cycling amplification for label-free and rapid detection of miRNA

Mengxu Sun, Yanxin Zhang, Juan Xie, Ya Zhang, Ting Huang, Minmin Li, Jin-Xiang Chen, Zong Dai, Jun Chen

Summary: This study developed a highly efficient and sensitive miRNA detection method by combining APE1-mediated isothermal target cycling amplification system with magnetic separation. The label-free and rapid detection of miRNA was achieved through the recognition and cleavage of AP probes by APE1, and the fluorescence measurement of G4/ThT. The method showed high specificity and sensitivity, and demonstrated its application in detecting miR-1246 in serum samples from breast cancer patients and normal people.

SENSORS AND ACTUATORS B-CHEMICAL (2024)

Article Chemistry, Analytical

Classification of circulating tumor cell clusters by morphological characteristics using convolutional neural network-support vector machine

Junhyun Park, Seongmin Ha, Jaejeung Kim, Jae-Woo Song, Kyung-A. Hyun, Tohru Kamiya, Hyo-Il Jung

Summary: In this study, a hybrid algorithm was developed for accurate classification of CTC clusters without immunofluorescence staining, providing a powerful tool for cancer diagnosis and prognosis.

SENSORS AND ACTUATORS B-CHEMICAL (2024)