Dentistry, Oral Surgery & Medicine

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Article Dentistry, Oral Surgery & Medicine

A case of extremely rare mandibular osteoblastoma successfully treated with functional reconstruction

Masashi Tamura, Yasutaka Hoshimoto, Shohei Seta, Yasuhiro Nakanishi, Masashi Sasaki, Takayuki Aoki, Kazunari Karakida, Yoshihide Ota

Summary: Osteoblastoma is a rare bone tumor that often occurs in the maxillofacial region, primarily the posterior mandible. Swelling and pain are common symptoms, but some cases are asymptomatic. Diagnosis can be challenging due to similarities with other diseases. Complete resection is the preferred treatment.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

CD20+cells blockage by rituximab delays wound healing in oral traumatic ulcers in rats

Antonio Alexandre Coelho, Rute Romao Carvalho, Ana Luiza Muniz, Andre Alves Crispim, Anderson Maia Meneses, Carla Welch da Silva, Dayrine Silveira de Paula, Ana Paula Negreiros Nunes Alves, Fabricio Bitu Sousa, Paulo Goberlanio de Barros Silva

Summary: The study aimed to evaluate the role of CD20 + cells in the healing process of oral traumatic ulcers (OTU) in rats. The results showed that blocking CD20 + cells with anti-CD20 rituximab (RTX) reduced cell migration, acute inflammation, and wound healing in OTU.

ARCHIVES OF ORAL BIOLOGY (2024)

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Article Oncology

Development of machine learning models for the prediction of long-term feeding tube dependence after oral and oropharyngeal cancer surgery

Andrea Costantino, Claudio Sampieri, Gian Marco Pace, Bianca Maria Festa, Luca Cerri, Giorgio Gregory Giordano, Michael Dale, Giuseppe Spriano, Giorgio Peretti, Armando De Virgilio

Summary: This study aimed to predict the necessity of enteral nutrition at 28 days after surgery in patients with head and neck cancers. The results showed that the machine learning models had optimistic accuracy in predicting the need for enteral nutrition, but had moderate sensitivity.

ORAL ONCOLOGY (2024)

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Article Oncology

Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma

Emily Capone, Vittoria Perrotti, Ilaria Cela, Rossano Lattanzio, Lucrezia Togni, Corrado Rubini, Vito Carlo Alberto Caponio, Lorenzo Lo Muzio, Martina Colasante, Francesco Giansanti, Rodolfo Ippoliti, Stefano Iacobelli, Michael J. Wick, Nicole Spardy Burr, Gianluca Sala

Summary: This study explores the potential of galectin-3 binding protein (LGALS3BP) as a novel target for antibody-drug conjugate (ADC) therapy in adenoid cystic carcinoma (ACC). The results show that LGALS3BP is highly expressed in ACC tissues and treatment with anti-LGALS3BP ADC leads to durable tumor growth inhibition in animal models.

ORAL ONCOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

An oral lesion as a primary manifestation of Burkitt lymphoma; imaging findings and complications of treatment: A case presentation

Safa Motevasseli, Niousha Roudbari, Zahra Dalili Kajan, Armin Gholamhosseinzadeh, Melika Roudbari, Emad Taghizadeh, Bahram Darbandi

Summary: This case describes a 9-year-old boy with a mass in the palatal and buccal aspect of the left maxillary alveolar ridge. He was diagnosed with Burkitt lymphoma, with visceral involvement. The maxillofacial surgeon excised the maxillary mass and the patient received chemotherapy.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Supraclavicular lymphangioma presenting in the sixth decade of life: A case report

Christina Matl, Lacey Durham, Borislav A. Alexiev, James C. Wang

Summary: This article presents an extremely rare case of an adult supraclavicular lymphangioma. The patient underwent surgical removal of a cystic mass in the supraclavicular region, which was confirmed to be a cavernous lymphangioma through histopathology. Although supraclavicular lymphangiomas in adulthood are uncommon, they should not be disregarded as a potential cause of supraclavicular masses.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Histologic and proteomic profile of two methods to decellularize human dental pulp tissue

Viviane Martins dos Santos Ribeiro, Mauricio Gonsalves da Costa Sousa, Paula Ribeiro Garcia, Lucas Souza dos Santos, Eliza Carla Barroso Duarte, Jose Raimundo Correa, Carlos Alberto Labate, Thais Regiani Cataldi, Rosiane Andrade da Costa, Marcelo Henrique Soller Ramada, Juliana Lott de Carvalho, Taia Maria Berto Rezende

Summary: This study compared the structural and proteomic architecture of decellularized human dental pulp using two different protocols. The results showed that the ECM preserved in the MG protocol was more intact. Proteomic analysis revealed that the MG protocol maintained around 69.56% of the proteins identified in the untreated pulp tissue, while the SG protocol only maintained 28.26%.

ARCHIVES OF ORAL BIOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy

Jinjin Lu, Lixin Zhang, Ningxin Zhu, Dan Wang, Fei Xie, Man Qin, Yuanyuan Wang

Summary: The study investigated the effects of varying glucose concentrations on the proliferation and senescence of SHED and hBMSC. It was found that high glucose levels promoted proliferation in both cell types, but delayed senescence in SHED through autophagy inhibition and accelerated senescence in hBMSC. Additionally, the glycolysis in SHED was enhanced under high glucose culture conditions compared to hBMSC.

ARCHIVES OF ORAL BIOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Head and neck cancer stem cell maintenance relies on mTOR signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2)

Luciana O. Almeida, Luan Cesar Silva, Carolina Emerick, Juliana Amorim dos Santos, Rogerio M. Castilho, Cristiane H. Squarize

Summary: This study found that the loss of PTEN signaling increases the population of HNSCC CSCs, which can be targeted by rapamycin. However, a deficiency in mTORC2 can lead to problematic selection of the parasphere CSC subtype.

ARCHIVES OF ORAL BIOLOGY (2024)

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Article Oncology

Transoral robotic surgery in oropharyngeal squamous cell carcinoma: A comparative study between da Vinci Single-Port and da Vinci Xi systems

Andrea Costantino, Claudio Sampieri, Piero Giuseppe Meliante, Armando De Virgilio, Se-Heon Kim

Summary: This study compares the outcomes of transoral resections using the da Vinci SP and da Vinci Xi systems for oropharyngeal squamous cell carcinoma (OPSCC). The results indicate that the da Vinci SP system has advantages in terms of reduced docking and console times, as well as improved rates of wide negative resection margins. However, there were no significant differences in complication rates or postoperative functional outcomes between the two systems.

ORAL ONCOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

The role of podoplanin inhibitors in controlling oral cancer progression

Engku Nasiha Engku Ngah Sayuddin, Muhammad Taher, Mohd Hafiz Arzmi, Nor Aszlitah Burhanudin, Muhamad Ashraf Rostam

Summary: This article reviews the role of podoplanin in oral cancer and its potential as a therapeutic agent. High expression of podoplanin has been observed in oral cancer and pre-cancerous lesions, suggesting that inhibitors targeting podoplanin could be effective in treating oral cancer.

ARCHIVES OF ORAL BIOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Patients' experience with teledentistry compared to conventional follow-up visits in TMD clinic: A pilot study

Alaa Husni Qari, Raghad Mohammed Alharbi, Shahd Saud Alomiri, Banan Nasser Alandanusi, Lina Ayman Mirza, Mohammad Hasan Al-Harthy

Summary: The study compares the experience of patients seen using teledentistry with traditional Orofacial Pain and TMD visits. Results indicated a borderline difference in effectively using teledentistry for follow-ups among different age groups, but no significant differences were found in patients' experience between virtual and conventional visits. This suggests that high-quality dental care services can be provided remotely without adversely affecting patient experience or quality of care.

JOURNAL OF DENTISTRY (2024)

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Article Dentistry, Oral Surgery & Medicine

Segmental mandibulectomy for mandibular osteoradionecrosis in an older adult with underweight status

Junya Kusumoto, Yuka Hayase, Yuriko Susukida, Takumi Sato, Akiko Sakakibara, Masaya Akashi

Summary: Refractory osteomyelitis can lead to complications in advanced mandibular osteoradionecrosis (ORN), such as recurrent cellulitis and pathological fractures. The optimal treatment for such conditions has not been established yet. Difficulty in intake and severe pain caused by mandibular ORN may result in malnutrition and underweight. Refeeding syndrome (RFS) should be considered in invasive surgical procedures.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Molecular and histopathological findings in malignant transformation of proliferative verrucous leukoplakia that was successfully controlled for 15 years

Suguru Hirota, Yukio Yoshioka, Fumitaka Obayashi, Sachiko Yamasaki, Koichi Koizumi, Souichi Yanamoto

Summary: This study identified new molecular and histopathological features of the malignant transformation of proliferative verrucous leukoplakia. The results showed the important role of Wnt-related oncogenes and the suppressing effect of the p53-p21 signaling pathway on carcinogenesis in the precancerous stage.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2024)

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Article Dentistry, Oral Surgery & Medicine

Effects of alpha-tocopherol antioxidant on fracture strength and adhesion of endodontically treated teeth restored after dental bleaching

Natalia Marcomini, Maria Carolina da Costa Albaricci, Joatan Lucas de Sousa Gomes Costa, Joao Felipe Besegato, Eduardo Fernandez Godoy, Andrea Abi Rached Dantas, Milton Carlos Kuga

Summary: This study evaluated the effects of different concentrations of alpha-tocopherol in gel on fracture strength, hybrid layer formation, and microtensile bond strength of teeth treated with endodontic treatment and bleached with 40% hydrogen peroxide. The results showed that 15% alpha-tocopherol effectively reversed the detrimental effects of bleaching on hybrid layer formation and bond strength.

EUROPEAN JOURNAL OF ORAL SCIENCES (2023)

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Article Dentistry, Oral Surgery & Medicine

Alterations in oxidative stress biomarkers and helper T-cell subgroups in patients with periodontitis and IgA nephropathy

Jinfeng Li, Yanjun Zhang, Hao Lu, Zhiwei Li, Hui Luo, Qianqiu Ou, Xiaotao Chen

Summary: This study aimed to investigate the changes in oxidative stress levels and helper T lymphocyte (Th) subsets in patients with periodontitis and IgA nephropathy (IgAN), and to determine their relationship.

JOURNAL OF PERIODONTAL RESEARCH (2023)

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Article Dentistry, Oral Surgery & Medicine

Allogeneic versus autogenous shell technique augmentation procedures: a prospective-observational clinical trial comparing surgical time and complication rates

Jochen Tunkel, Frederik Hoffmann, Yannik Schmelcher, Anita Kloss-Brandstaetter, Peer W. Kaemmerer

Summary: Compared to the autogenous technique, allogeneic shell augmentation has a shorter surgical time and a similar rate of intra- and postoperative complications as autogenous bone. Together with its promising clinical results, this technique can be recommended.

INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY (2023)

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Article Dentistry, Oral Surgery & Medicine

The association between rheumatoid arthritis and masticatory muscles through the utilization of diffusion-weighted magnetic resonance imaging

Naohisa Hirahara, Kotaro Ito, Hirotaka Muraoka, Eri Sawada, Tomohiro Komatsu, Takashi Kaneda

Summary: This study investigated the association between rheumatoid arthritis (RA) and masticatory muscles by analyzing the apparent diffusion coefficient (ADC) obtained from diffusion-weighted magnetic resonance imaging (DW-MRI). The results revealed significant differences in the condition of the masticatory muscles between RA patients and the control group, suggesting the potential of using ADC measured through DWI for evaluating the association between masticatory muscles and RA.

ORAL SCIENCE INTERNATIONAL (2023)

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Article Dentistry, Oral Surgery & Medicine

Validity and reliability of artificial intelligence chatbots as public sources of information on endodontics

Hossein Mohammad-Rahimi, Seyed AmirHossein Ourang, Mohamad Amin Pourhoseingholi, Omid Dianat, Paul Michael Howell Dummer, Ali Nosrat

Summary: This study evaluated and compared the validity and reliability of responses provided by GPT-3.5, Google Bard, and Bing to frequently asked questions in the field of endodontics. The findings showed that GPT-3.5 provided more credible information compared to Google Bard and Bing.

INTERNATIONAL ENDODONTIC JOURNAL (2023)

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Article Dentistry, Oral Surgery & Medicine

The influence of guide stabilizers and their application sequences on trueness and precision of surgical guides in free end situations: An in vitro analysis

Runheng Liu, Ruidi Xia, Linjun Zhang, Xuejing Gan, Cuijun Li, Quan Liu, Zhuofan Chen, Zetao Chen

Summary: This study evaluated the impact of guide stabilizers and their application sequences on implant placement accuracy in cases of multiple teeth loss at the free end. The results showed that using guide stabilizers and applying them in a specific sequence can significantly improve the precision of implant placement.

CLINICAL ORAL IMPLANTS RESEARCH (2023)

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