Chemistry, Organic

Review Chemistry, Applied

Molecular dynamics simulation techniques and their application to aroma compounds/cyclodextrin inclusion complexes: A review

Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke

Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

β-Glucan-conjugated anti-PD-L1 antibody enhances antitumor efficacy in preclinical mouse models

Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu

Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Robust and highly reactive membranes for continuous disposal of chemical warfare agents: Effects of nanostructure and functionality in MOF and nanochitin aerogel composites

Jin Young Seo, Younghan Song, Jung-Hyun Lee, Jongbeom Na, Kyung-Youl Baek

Summary: A novel green-fabrication method using UiO-66 catalysts and amine-functionalized chitin nanofibers (ChNFs) was proposed for preparing durable and highly reactive membranes for decomposing chemical warfare agents. The resulting membranes showed stable loading and strong interaction between ChNFs and UiO-66, leading to excellent catalytic activity and recyclability.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Fermentation characteristics and prebiotic potential of enzymatically synthesized butyryl-fructooligosaccharides

Zixin Yang, Diming Tan, Weiwen Chen, Jun Hu, Rui Huang, Xiyang Wu, Milen I. Georgiev, Weibin Bai, Lingmin Tian

Summary: Enzymatically synthesized butyryl-FOSs show potential as novel prebiotics, as they can modulate gut microbiota by promoting the growth of beneficial bacteria and reducing harmful ones. The supplementation of B-FOSs resulted in a significant increase in butyric acid levels during fermentation.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Silver nanowire-infused carbon aerogel: A multifunctional nanocellulose-derived material for personal thermal management

Meiling Zhang, Yinan Fan, Ni Wang, Hongguo Gao, Lei Zhang, Yanjiao Zhao, Lifang Liu

Summary: Personal thermal management textiles for outdoor activities are important for energy-saving and thermal comfort. Carbonized cellulose nanofiber aerogel with silver nanowires coating shows excellent thermal insulation and heating performance. It also has low emissivity and high solar absorptivity, making it suitable for various outdoor conditions. Additionally, it possesses breathability, permeability, and electromagnetic shielding characteristics, making it a great candidate for advanced wearable textiles.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Multiscale structure of cellulose microfibrils in regenerated cellulose fibers

Jiliang Liu, Herbert Sixta, Yu Ogawa, Michael Hummel, Michael Sztucki, Yoshiharu Nishiyama, Manfred Burghammer

Summary: Cellulose in solution can be assembled into textile fibers with different mechanical properties using wet-spinning or dry-jet wet spinning. Scanning X-ray microdiffraction reveals the structure of regenerated fibers, which consist of microfibrils in the core region. Ioncell fibers have better structural regularities and distinct morphologies of elementary fibrils, resulting in enhanced mechanical properties and wet strength compared to Viscose fibers.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

In situ injectable thermoresponsive nanocomposite hydrogel based on hydroxypropyl chitosan for precise synergistic calcium-overload, photodynamic and photothermal tumor therapy

Zhiyi Qian, Nuoya Zhao, Sicheng Xu, Weizhong Yuan

Summary: This study investigates a strategy for precise and synergistic therapies of tumors using injectable and self-healable hydrogel encapsulating specific fluorescent substances and nanoparticles, enabled by near infrared irradiation. The results show promising prospects for precise and efficient treatment of tumors.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

A highly stretchable, adhesive, and antibacterial hydrogel with chitosan and tobramycin as dynamic cross-linkers for treating the infected diabetic wound

Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan

Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Caffeic acid-grafted chitosan/sodium alginate/nanoclay-based multifunctional 3D-printed hybrid scaffolds for local drug release therapy after breast cancer surgery

Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song

Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Inorganic & Nuclear

Platinated azulenes: Structures and electronic spectroscopy

Van Ha Nguyen, John H. K. Yip

Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.

JOURNAL OF ORGANOMETALLIC CHEMISTRY (2024)

Review Chemistry, Applied

Opportunities and challenges of fucoidan for tumors therapy

Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu

Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Micro assembly strategies for enhancing solid-state emission of cellulose nanocrystals and application in photoluminescent inks

Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang

Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Enhanced porous membrane fabrication using cellulose acetate and citric acid: Improved structural integrity, thermal stability, and gas permeability

Chaeyeon Lee, Sojeong Lee, Sang Wook Kang

Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Valorization of shrimp processing waste-derived chitosan into anti-inflammatory chitosan-oligosaccharides (CHOS)

Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink

Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Enzymatically-derived oligo-carrageenans interact with α-Gal antibodies and Galectin-3

Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel

Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Preparation of crosslinked starches with enhanced and tunable gel properties by the cooperative crosslinking-extrusion combined modification

Wenguang Wei, Min Wu, Weike Ren, Haoze Yu, Dongyu Sun

Summary: Due to the low degree of crosslinking, the application of citric acid crosslinking modification is restricted. In this study, a novel ion-esterification cooperative crosslinking-extrusion combined (CCEC) modification approach was proposed to improve the strength and tunable gel characteristics of citric acid-crosslinked starch. The results showed that the CCEC-modified starch had a significantly higher elastic modulus and a denser porous structure. By changing the cation concentration, the rheological characteristics of the gel could be efficiently controlled.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Thermally-activated gelatin-chitosan-MOF hybrid aerogels for efficient removal of ibuprofen and naproxen

Minseok Kim, Lewis Kamande Njaramba, Yeomin Yoon, Min Jang, Chang Min Park

Summary: This study successfully synthesized a thermally-activated gelatin-chitosan and amine-functionalized metal-organic framework aerogel for efficient removal of NSAIDs. The synthesized aerogel was characterized using various tools and its adsorption performance and mechanism were verified through experiments.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Advances in tissue engineering of gellan gum-based hydrogels

Shanyi Wu, Rongjun Xiao, Yong Wu, Laijun Xu

Summary: This review discusses the emerging advances and applications of Gellan gum (GG)-based hydrogels in tissue engineering, highlighting their potential in bone, cartilage, nerve, and retina tissue engineering. The review also explores the use of GG-based hydrogels as bioink components for 3D bioprinting.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

Rapid and convenient synthesis of green ammonium-modified chitosan composite sponge with the existence of ascorbic acid for highly efficient removal of Congo red (CR)

Keyu Ren, Yanan Fan, Guozheng Xing, Mengge Zhai, Jie Sheng, Yishan Song

Summary: A new green composite sponge, ACS-CIT, made of chitosan modified with ammonium ascorbate, was synthesized in just 10 minutes. This sponge exhibited significantly enhanced adsorption performance for CR, with increased adsorption capacities. The adsorption mechanism can be summarized as the generation of more hydrogen bonds, electrostatic attraction, and intra particle diffusion, resulting in a significant increase in its adsorption capacity. The prepared ACS-CIT showed excellent CR removal performance even in the presence of multiple interfering factors coexisting in the simulated wastewater.

CARBOHYDRATE POLYMERS (2024)

Article Chemistry, Applied

3-Diethylaminopropyl isothiocyanate modified glycol chitosan for constructing mild-acid sensitive electrospinning antibacterial nanofiber membrane

Weiyang Shen, Yongxin Wang, Yali Li, Zongyao Cui, Yitong Yang, Honglu Shi, Chenfeng Xu, Tingjie Yin

Summary: In this study, a mild acid-responsive nanofiber membrane was fabricated, loaded with ciprofloxacin to prevent bacterial infection and promote wound healing.

CARBOHYDRATE POLYMERS (2024)