Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Hongkun Li, Qianqian Cai, Yali Xue, Guifen Jie
Summary: A unique dual-mode biosensor based on hydrogen-bonded organic frameworks (HOF-101) was constructed for ultrasensitive detection and imaging of oxytetracycline (OXY), using polydopamine nanoparticles (PDAs) as quencher. PDAs, with good biocompatibility and light absorption ability, were introduced onto the surface of HOF-101 to quench its electro-chemiluminescence (ECL) and photoelectrochemical (PEC) signals, achieving ultrasensitive detection of OXY.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Xiao Fang, Siqi Wang, Qingqing Wang, Jun Gong, Li Li, Helin Lu, Ping Xue, Zhanhong Ren, Xiaobo Wang
Summary: In this study, a new fluorescent probe, BA-Cyclen-Cu, was designed and synthesized for sensitive and rapid detection of aqueous hydrogen sulfide (H2S). The probe exhibited good membrane permeability, low toxicity, and lysosome-targeting ability in living cells. The results demonstrated the potential applications of the probe in detecting both exogenous and endogenous H2S in various cell types and serum samples.
Article
Chemistry, Analytical
Victor Hugo Calvacanti Ferreira, Carlos Alberto Teixeira, Leandro Wang Hantao, Julian Eduardo Ballen Castiblanco
Summary: In this study, an alternative method for classifying produced water (PW) samples using a one-class classifier (OCC) model was proposed. Headspace solid-phase microextraction (HS-SPME) combined with comprehensive two-dimensional gas chromatography (GCxGC) were used to obtain total oil and grease (TOG) profiles from PW. The OCC model approach showed outstanding results in classifying PW samples according to environmental regulations.
Article
Chemistry, Analytical
Zhe Liu, Xichao Mo, Shuhao Tian, Jie Chen, Yanpeng Liu, Haiyang Wu, Yawei Zhao, Yanrong Wang, Shanglong Peng
Summary: This study demonstrates the fabrication of Co3O4/MX7.5 heterojunction using electrostatic adsorption and calcination strategies, and shows its potential for detecting ethanol at a relatively low temperature with long-term stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Solaleh Ghateii, Amir Jahanshahi
Summary: Recent advances in microfluidic paper-based analytical devices have shown great potential for point-of-care testing, particularly for monitoring glucose levels in diabetes patients. However, the practical application of smartphone-coupled devices has been hindered by variability in ambient lighting conditions. In this study, a machine learning-based algorithm and flash/no-flash technic were developed to address the issue, resulting in accurate monitoring of plasma glucose levels across a wide range and in various lighting conditions.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yue Wu, Rui Liu, Zediao Huang, Hengye Chen, Xiangyu Zhao, Yanmin Rao, Rongxian Bai, Wanjun Long, Jian Yang, Wei Lan, Haiyan Fu
Summary: In this study, a dual-channel colorimetric sensor was constructed to identify the authenticity and origin of Atractylodis Macrocephalae Rhizoma (AMR) using metal ions mediated color transformation of gold nanoparticles (AuNPs). The sensor accurately classified AMR samples from different origins and their counterfeits based on significantly different color transformations.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Xiaojie Qin, Binqi Wei, Yuanhang Xiang, Hao Lu, Fengfei Liu, Xinchun Li, Fan Yang
Summary: This study utilizes the coordination between exosomes and metal-organic frameworks to develop an ultrasensitive detection method for tumor-derived exosomes. The method is highly specific and fast, allowing for the profiling of different cancer types and accurate diagnosis in a clinical setting. This strategy provides new opportunities for functional materials assembly and precision diagnostics.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Shikha Shrivastava, Debashrita Mahana, Simran Nehra, Sunil Gangwar, Sandeep Singh, C. S. Yadav, Senthil Kumar Muthusamy, Anjana Dogra
Summary: In this study, the perovskite Barium Stannate (BaSnO3) thin films were investigated for CO gas sensing application. The electrical properties and gas sensing response of BaSnO3 thin films were improved by reducing the film thickness. The 90 nm thick film exhibited a higher gas sensing response at a lower temperature due to the presence of numerous grains and grain boundaries facilitating the adsorption and desorption of oxygen species.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Xuelin Zhang, Hui Dong, Hui Zhou, Yueyuan Li, Qing Liu, Hongyou Cui, Shujun Wang, Yueyun Li, Qin Wei
Summary: By regulating the surface motifs of metal nano-clusters (MNCs) based on aggregation-induced emission (AIE) strategy, a highly efficient luminescent probe AuAg NCs was designed. The introduction of Ag(I) resulted in denser surface patterns, reducing the non-radiative energy dissipation. Additionally, the spontaneous catalytic cycle amplification strategy improved the electrochemiluminescence (ECL) efficiency of AuAg NCs. The biosensor showed a wide linear relationship range and low detection limit using cardiac troponin I as a model.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feihu Li, Junjie Jing, Jinkun Li, Shuni Li, Siyu Ye, Xinru Song, Zili Zhan, Yeguang Zhang
Summary: In this study, ZnO-SnO2 heterojunction three-dimensional inverse opal photonic crystal balls (IOPB) were fabricated via rapid and liquid waste-free spray drying. The IOPBs showed higher response and faster response/recovery times compared to pure SnO2 sensors, as well as good selectivity and long-term stability.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yu Jin Park, Dong-Yeon Song, Dong-Myung Kim
Summary: Advancing expeditious and highly responsive in vitro diagnostic techniques is crucial for ensuring the effectiveness of disease prevention and control measures. This study utilizes the translational machinery to transform target nucleic acids into easily quantifiable proteins, offering a versatile pathway for adaptable and cost-effective nucleic acid testing.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yukun Wang, Guoming Ma, Dan Gao, Yuan Wang, Yangyang Xie, Xunbo Gao, Houxian Du, Junting Ji
Summary: This paper proposed a methane sensor based on the evanescent field of the non-adiabatic tapered optical fiber (NATOF) for high-sensitivity in-situ detection of transformer oil-dissolved methane. The sensor exhibited a detection sensitivity of 9.8 pm/ppm and a detection limit of 2.35 ppm, with excellent reversibility validated through cyclic experiments.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Mustafa Sen, Merve Oguz, Ipek Avci
Summary: A non-toxic, flexible, low-cost, and disposable multiwalled carbon nanotube (MWCNT)-based screen-printed electrode (SPE) was developed for non-invasive health monitoring applications. The electrode demonstrated excellent electrochemical behavior and is expected to contribute to wearable sensor technology.
Article
Chemistry, Analytical
Ruimei Zhang, Yuxin Guo, Jiawei Huang, Hongchang Li, Ruizhi Wen, Wenlei Wang
Summary: This study established a rapid method for the detection of tetracycline (TC) by utilizing sodium alginate-protected gold nanoclusters (SA-AuNCs) and europium ions (Eu3+). The proposed method showed a linear relationship over a wide range of TC concentrations, with a low detection limit and high recovery rates. Additionally, color information extracted from fluorescence images taken with a smartphone was analyzed using MATLAB, enabling semi-quantitative detection of TC in real samples without the need for time-consuming pretreatment or expensive instruments.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Hui Heng, Qingyang Gu, Haibo Jin, Ping Shen, Jiaxin Wei, Xinyu Er, Jia Sun
Summary: A novel ratiometric fluorescence nanoprobe has been developed to selectively and sensitively detect tryptophan enantiomers. The nanoprobe shows excellent linearity, selectivity, and specific recognition, and can achieve visual detection in actual samples.
