Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Zi Liu, Guoxiang Rong, Hui Dong, Yintang Zhang, Maotian Xu, Baoxian Ye, Yanli Zhou
Summary: This work introduces a lateral moving multi-pedal DNA tetrahedron machine (MTM) coupled with a dual-signal output system for ultrasensitive target DNA analysis. The lateral motion mode of the DNA machine coalescing with a ratiometric system improves the movement efficiency and shortens the time fragment, resulting in high sensitivity and accuracy for early diagnosis.
Article
Chemistry, Analytical
Chengyuan Wu, Yuanyuan Yue, Baicheng Huang, Hanxu Ji, Lina Wu, He Huang
Summary: In this study, we utilized Pd@PCN-222 nanozyme as a reporter for the CRISPR system and achieved outstanding detection of ochratoxin A, avoiding the need for traditional pre-amplification. We also developed a microfluidic electrochemical chip for on-site detection.
Article
Chemistry, Analytical
Jiyao Wang, Hai Chen, Yiyuan Ling, Chong Zhang, Haobo Zhou, Xiaohao Wang, Kai Ni
Summary: This article proposes a novel method to address the limitations of the conventional ion gate in IMS systems, which effectively reduces trailing edge deformation, improves resolving power and signal intensity, and achieves reverse discrimination effect.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
Article
Chemistry, Analytical
Laura Gutierrez-Galvez, Daniel Garcia-Fernandez, Melisa del Barrio, Monica Luna, Inigo Torres, Felix Zamora, Cristina Navio, Paula Milan-Rois, Milagros Castellanos, Melanie Abreu, Rafael Canton, Juan Carlos Galan, Alvaro Somoza, Rodolfo Miranda, Tania Garcia-Mendiola, Encarnacion Lorenzo
Summary: In this study, a highly sensitive method based on biocatalyzed electrochemiluminescence approach was developed. The method utilizes few-layer bismuthene as a platform for immobilizing tetrahedral DNA nanostructures that are specifically designed to detect a specific gene sequence of SARS-CoV-2. The method exhibits a low limit of detection and a wide linear range, and can be used to directly detect the virus in samples from COVID-19 patients.
Article
Chemistry, Analytical
Samira Ghasemi, Jahan Bakhsh Raoof, Milad Ghani, Reza Ojani
Summary: In this study, rod-like ZIF-8 was prepared using Escherichia coli bacteria as a bio-template and used for microextraction. A new sorbent was prepared using electrospun nanofiber mats and demonstrated satisfactory performance in the analysis of benzoylurea insecticides. The extraction method was optimized using experimental design strategy, and the model analytes were detected using high-performance liquid chromatography.
Article
Chemistry, Analytical
Wenyue Gao, Hongye Yang, Yifei Zhang, Dexin Gao, Chi Wu
Summary: A novel and efficient electrochemiluminescence (ECL) sensing strategy and solid-state ECL sensor were proposed for the detection of trimethylamine oxide (TMAO) in marine species. The developed sensor showed good performance in various species of seafood samples and provided a promising strategy for TMAO detection.
Article
Chemistry, Analytical
Jiaqi Liu, Chunning Chen, Jiaxin Lu, Yalei Wang, Jingtong Zhai, Hongkun Zhao, Nan Lu
Summary: A method to reduce defects in the assembly of Ag nanocubes by using a patterned substrate as a template is reported. The prepared substrate, with high-density and uniform hotspots, exhibits high sensitivity and reproducibility as a SERS substrate that can be used for analyzing various analytes.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Xinpu Zhang, Zeliu Li, Wen Yan, Ang Li, Fenglin Zhang, Xiaotong Li, Mengdi Lu, Wei Peng
Summary: Prism-based surface plasmon resonance (SPR) system is a leading candidate concept for scale application and commercial solution. By optimizing and integrating the optical system, a miniaturized and customizable SPR system has been developed to meet the various needs of different users and application scenes.
Article
Chemistry, Analytical
Qing Chen, Xiao-nan Zhang, Guo-yu Ding, Yu-fei Ma, Ming-sheng Zhou, Yang Zhang
Summary: In this study, a pH-responsive drug delivery system was designed and prepared, utilizing trastuzumab-coupled mesoporous zeolitic imidazolate framework-8 (ZIF-8) as the carrier. The system exhibited high drug loading and good biocompatibility, with a pH-triggered drug release mechanism. Cellular uptake tests showed enhanced uptake by cancer cells overexpressing HER2. Animal experiments demonstrated the potential of the system for tumor inhibition. Overall, this smart drug delivery system shows promise for efficient and controllable cancer treatment applications.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Camila Diana Lima, Larissa Magalhaes de Almeida Melo, Luciano Chaves Arantes, Nathalia dos Santos Conceicao, Izabela de Franca Schaffel, Lara Lima Machado, Rafael de Queiroz Ferreira, Wallans Torres Pio dos Santos
Summary: This study presents the electrochemical detection of 3',4'-Methylenedioxy-N-tert-butylcathinone (MDPT) using screen printed electrodes modified with carbon nanofibers. The proposed method showed high selectivity and stability for MDPT determination, making it a fast and simple screening method in forensic analysis.
Article
Chemistry, Analytical
Bangfeng Wang, Zetai Liu, Hong Yan, Mingyu Zhang, Shibo Li, Shunji Li, Hufei Duan, Hongjia Kang, Peng Chen, Wei Du, Yiwei Li, Xiaojun Feng, Bi-Feng Liu
Summary: Due to the increasing challenge of emerging infections, the development of portable health platforms, such as smartphone-based centrifugal mHealth platforms, has gained significance. These platforms offer advantages like portability, ease of use, and automated analysis of results. In this study, a daisy-shaped quick response chip is developed for hematocrit measurement, and a customized recognition algorithm enables non-experts to perform hematocrit measurement using smartphones.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Review
Archaeology
S. Sylaiou, P. Dafiotis, D. Koukopoulos, K. Koukoulis, R. Vital, A. Antoniou, Chr. Fidas
Summary: This manuscript discusses the growing importance of Extended Reality (XR) in art exhibitions. It explores the technologies used, design issues, evaluation metrics, and aims of XR exhibitions. The research focuses on the current types of technologies used, primary design considerations, and methods to enhance user experience. The paper also examines evaluation criteria and the use of virtual humans for increased engagement. Additionally, it thoroughly discusses parameters affecting user experience and offers suggestions for optimizing design and future directions.
JOURNAL OF CULTURAL HERITAGE
(2024)
Article
Archaeology
Justin J. L. Kimball, Ruben With, Christian Lochsen Rodsrud
Summary: Micro-CT (μCT) has been increasingly used in the cultural heritage sector to understand past cultures and their materials. In the case of the Gjellestad ship from the Viking Age, μCT was used to document and conserve the deteriorated organic and metallic materials. A georeferencing system was developed to retain important stratigraphic and position information, allowing for spatial positioning using 3D GIS. The use of μCT has shown positive impact on the documentation, conservation, and reconstruction of cultural heritage.
JOURNAL OF CULTURAL HERITAGE
(2024)
Article
Archaeology
Carlo Battini, Umberto Ferretti, Giorgia De Angelis, Roberto Pierdicca, Marina Paolanti, Ramona Quattrini
Summary: This research presents a method for recognizing historical building elements using a deep learning system. By leveraging synthetic point clouds to generate 3D models, the proposed approach achieves high accuracy in the experiments conducted on a newly synthetic dataset.
JOURNAL OF CULTURAL HERITAGE
(2024)
