Journal
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
Volume 94, Issue 8, Pages 1109-1123Publisher
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.2009.005983
Keywords
B-cell non-Hodgkin's lymphoma; extranodal marginal zone B-cell lymphoma; immunoglobulin; B-cell antigen receptor; inflammation; lymphoid tissue neogenesis
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Chronic autoimmune or pathogen-induced immune reactions resulting in lymphoid neogenesis are associated with development of malignant lymphomas, mostly extranodal marginal zone B-cell lymphomas (MZBCLs). In this review we address (i) chemokines and adhesion molecules involved in lymphoid neogenesis, (ii) the autoimmune diseases and pathogens which are associated with development of B-cell lymphomas, (iii) the molecular mechanisms involved in the initiation and progression of MZBCL; and (iv) 'potential' mouse models for MZBCL.
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