Journal
GYNECOLOGICAL ENDOCRINOLOGY
Volume 29, Issue 2, Pages 113-115Publisher
INFORMA HEALTHCARE
DOI: 10.3109/09513590.2012.706669
Keywords
Assisted reproductive technology; endometriosis; placenta previa; tubal disease
Funding
- Ministry of Health, Labour and Welfare
- Ministry of Education, Culture, Sports, Science and Technology
- Grants-in-Aid for Scientific Research [22791517, 23592395] Funding Source: KAKEN
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Although assisted reproductive technology (ART) is suspected to increase the risk of placenta previa, a life-threatening complication of pregnancy, the reason is poorly understood. We recruited consecutive 318 pregnancies conceived by ART in our clinic and examined relation of ten variables, i.e. maternal age, gravidity, parity, male or female fetus, previous abortion, previous cesarean delivery, endometriosis, ovulatory disorder, tubal disease, and male infertility, to placenta previa, by logistic regression analysis. As a result, we found that endometriosis (odds ratio = 15.1; 95% CI = 7.6-500.0) and tubal disease (odds ratio = 4.4; 95% CI = 1.1-26.3) were significantly associated with placenta previa. It would be preferable to take the increased risk of placenta previa into account in treating ART pregnancy with endometriosis and tubal disease.
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