Journal
GYNECOLOGICAL ENDOCRINOLOGY
Volume 27, Issue 2, Pages 128-133Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/09513590.2010.487612
Keywords
Gestational diabetes; metabolic syndrome; platelet-activating factor acetylhydrolase; gamma-glutaminyl transferase
Funding
- Fatih University [P53010909_1]
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Methods. The cross-sectional study included 36 women with history of GDM and 40 women with history of normal glucose tolerance in pregnancy (control group). Results. Compared to the controls, the GDM group had significantly higher mean values for serum glucose, insulin, HOMA-IR, triglyceride, GGT and plasma PAF-AH activity, and a statistically higher prevalence of MS. Within the GDM group, women diagnosed with MS had significantly higher PAF-AH activity than those without MS (p = 0.002). Conclusion. This is the first study to have shown that plasma PAF-AH activity and GGT levels may be significant for evaluating atherosclerosis risk and metabolic hepatic damage in women with history of GDM.
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