Dermatological complications and safety of anti-TNF treatments

It has been reported that tumour necrosis factor (TNF) inhibitors have adverse side-effects including infections, malignancies, demyelinating disease, and induction of autoimmune conditions. Dermatological complications of anti-TNF therapy include injection site reactions, cutaneous infections, allergic rashes, psoriasis, non-melanoma skin cancer (NMSC), and rare reports of lupus-like syndrome, erythema multiforme (EM), Steven's Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN).