4.8 Article

Copper-catalyzed C-C bond cleavage and intramolecular cyclization: an approach toward acridones

Journal

GREEN CHEMISTRY
Volume 15, Issue 1, Pages 76-80

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc36502b

Keywords

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Funding

  1. National Science Foundation of China [21102123]
  2. Hunan Province Department of Education [11C1208]
  3. Xiangtan University [KZ08018, KZ03011]

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A copper-catalyzed approach for the synthesis of acridones via C-C bond cleavage and intramolecular cyclization using air as the oxidant under neutral conditions is described. This transformation offers an alternative method to prepare medicinally important acridones and a new strategy for C-C bond cleavage.

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