Journal
GREEN CHEMISTRY
Volume 14, Issue 11, Pages 3157-3163Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc36095k
Keywords
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Funding
- National Natural Science Foundation of China [21172124]
- National Basic Research Science Foundation of China [2010CB126105]
- National Key Technologies RD Program [2011BAE06B05]
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A facile, efficient and environmentally-friendly protocol for the synthesis of alpha-acyloxy amides has been developed by ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions. This method provides several advantages over current reaction methodologies including a simpler work-up procedure, shorter reaction times and higher yields.
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