Journal
GREEN CHEMISTRY
Volume 14, Issue 8, Pages 2141-2145Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc35489f
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Funding
- National Science Foundation of China [21172092, 20102039]
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A novel and efficient TBHP/I-2-promoted oxidative coupling reaction of acetophenones with amines for the synthesis of alpha-ketoamides has been developed. The reactions proceeded smoothly at room temperature under metal-free and solvent-free conditions and generated the corresponding products in good yields.
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