4.8 Article

One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides under metal-free conditions

Journal

GREEN CHEMISTRY
Volume 14, Issue 12, Pages 3277-3280

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc36473e

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Funding

  1. National Natural Science Foundation of China [20902076, 21172185]
  2. Hunan Provincial Natural Science Foundation of China [11JJ1003, 12JJ7002]
  3. New Century Excellent Talents in University from Ministry of Education of China [NCET-11-0974]
  4. Scientific Research Foundation for Returned Scholars, Ministry of Education of China [2011-1568]

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One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides is disclosed. Various substituted carbazoles were obtained in moderate to good yields via a sequence of condensation, cyclization and dehydrogenation under metal free conditions using molecular oxygen as an oxidant.

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