Solvent- and catalyst-free synthesis of new hydroxylated trisubstituted pyridines under microwave irradiation

A facile solvent-and catalyst-free method for the synthesis of a series of new hydroxylated 2,4,6-trisubstituted pyridines under microwave irradiation was developed. The expected products were obtained through a simplified purification process without protection of the hydroxyl group. UV-Vis and fluorescence spectra of these conjugated multi-hydroxyl compounds were also investigated.